WNT2 Protein (AA 1-360) (GST tag)

Catalog No. ABIN1325356

Product Details

Target: WNT2 (Wingless-Type MMTV Integration Site Family Member 2 (WNT2))

Protein Type: Recombinant

Protein Characteristics: AA 1-360

Origin: Human

Source: Wheat germ

Purification tag / Conjugate: This WNT2 protein is labelled with GST tag.

Application: ELISA, Western Blotting (WB), Antibody Array (AA), Affinity Purification (AP)

Purpose: WNT2 (Human) Recombinant Protein (P01)

Sequence: MNAPLGGIWL WLPLLLTWLT PEVNSSWWYM RATGGSSRVM CDNVPGLVSS QRQLCHRHPD VMRAISQGVA EWTAECQHQF RQHRWNCNTL DRDHSLFGRV LLRSSRESAF VYAISSAGVV FAITRACSQG EVKSCSCDPK KMGSAKDSKG IFDWGGCSDN IDYGIKFARA FVDAKERKGK DARALMNLHN NRAGRKAVKR FLKQECKCHG VSGSCTLRTC WLAMADFRKT GDYLWRKYNG AIQVVMNQDG TGFTVANERF KKPTKNDLVY FENSPDYCIR DREAGSLGTA GRVCNLTSRG MDSCEVMCCG RGYDTSHVTR MTKCGCKFHW CCAVRCQDCL EALDVHTCKA PKNADWTTAT

Characteristics: Human WNT2 full-length ORF ( AAH29854, 1 a.a. - 360 a.a.) recombinant protein with GST-tag at N-terminal.

Purification: in vitro wheat germ expression system

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

Restrictions: For Research Use only

Handling

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -80 °C

Storage Comment: Best use within three months from the date of receipt of this protein.

References

Tsaousi, Williams, Lyon, Taylor, Swain, Johnson, George: "Wnt4/β-catenin signaling induces VSMC proliferation and is associated with intimal thickening." in: Circulation research, Vol. 108, Issue 4, pp. 427-36, (2011) (PubMed).

Habuchi, Nagai, Sugaya, Atsumi, Stevens, Kimata: "Mice deficient in heparan sulfate 6-O-sulfotransferase-1 exhibit defective heparan sulfate biosynthesis, abnormal placentation, and late embryonic lethality." in: The Journal of biological chemistry, Vol. 282, Issue 21, pp. 15578-88, (2007) (PubMed).

Target Details

Target: WNT2 (Wingless-Type MMTV Integration Site Family Member 2 (WNT2))

Alternative Name: WNT2 (WNT2 Products)

Synonyms: CG1916 Protein, D-wnt-2 Protein, DWnt-2 Protein, DWnt2 Protein, Dm DWnt2 Protein, Dm-2 Protein, Dmel\\CG1916 Protein, Dwnt-2 Protein, Wnt Protein, Wnt-2 Protein, dWnt2 Protein, wnt2 Protein, WNT2 Protein, irp Protein, Xwnt2 Protein, wnt-2 Protein, Xwnt-2 Protein, int1l1 Protein, 2610510E18Rik Protein, Int1l1 Protein, Irp Protein, Mirp Protein, Wnt2a Protein, INT1L1 Protein, IRP Protein, ZfWnt2 Protein, Wnt oncogene analog 2 Protein, Wnt family member 2 Protein, wingless-type MMTV integration site family member 2 Protein, wingless-type MMTV integration site family, member 2 Protein, Wnt2 Protein, wnt2 Protein, WNT2 Protein

Background: Full Gene Name: wingless-type MMTV integration site family member 2
Synonyms: INT1L1,IRP

Gene ID: 7472

Pathways: WNT Signaling