PSMD4/ASF Protein (AA 2-377)
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- Target See all PSMD4/ASF (Psmd4) Proteins
- PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2-377
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- SDS-PAGE (SDS)
- Cross-Reactivity
- Human
- Characteristics
- Human angiocidin (aa 2-377) is untagged.
- Purity
- >95 % (SDS-PAGE)
- Endotoxin Level
- <0.1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product Psmd4 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with 100 μL sterile water.
- Concentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Expiry Date
- 6 months
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- Target
- PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))
- Alternative Name
- Angiocidin (Psmd4 Products)
- Synonyms
- af-1 Protein, mcb1 Protein, pub-r5 Protein, rpn10 Protein, PSMD4 Protein, DDBDRAFT_0202512 Protein, DDBDRAFT_0232981 Protein, DDB_0202512 Protein, DDB_0232981 Protein, AF Protein, AF-1 Protein, ASF Protein, MCB1 Protein, Rpn10 Protein, S5A Protein, pUB-R5 Protein, xrpn10c Protein, Af1 Protein, Mcb1 Protein, angiocidin Protein, im:6912672 Protein, psmd4 Protein, wu:fc68c04 Protein, zgc:110247 Protein, proteasome 26S subunit, non-ATPase 4 Protein, 26S proteasome non-ATPase regulatory subunit 4 Protein, 26s proteasome non-atpase regulatory subunit 4 (26s proteasomeregulatory subunit s5a) Protein, proteasome 26S subunit, non-ATPase 4 L homeolog Protein, proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 Protein, proteasome 26S subunit, non-ATPase 4b Protein, psmd4 Protein, PSMD4 Protein, LOC100194679 Protein, psmD4 Protein, LOC100283637 Protein, Smp_000740.1 Protein, psmd4.L Protein, Psmd4 Protein, psmd4b Protein
- Background
- Angiocidin shows sequence similarity with proteasome components and is also being referred to as 26A proteasome regulatory subunit S5A. Angiocidin shows both matrix and cytoplasmic distribution. It binds to thrombospondin-1 and alpha2beta1 integrin, and it inhibits tumor progression and angiogenesis. Angiocidin is expressed in various types of cancer, such as hepatocellular carcinoma, prostate, lung, bladder, and melanoma cancers.
- Molecular Weight
- ~50kDa (SDS-PAGE)
- UniProt
- P55036
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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