FABP4 Protein (AA 1-132) (His tag)

Catalog No. ABIN1344005

Product Details

Target: FABP4 (Fatty Acid Binding Protein 4, Adipocyte (FABP4))

Protein Type: Recombinant

Protein Characteristics: AA 1-132

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This FABP4 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Cross-Reactivity: Human

Characteristics: Human FABP4 (aa 1-132) is fused at the C-terminus to a His-tag.

Purity: >90 % (SDS-PAGE)

Sterility: 0.2 μm filtered

Endotoxin Level: <1EU/μg purified protein (LAL test, Lonza).

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.2μm-filtered solution in 55 mM TRIS-Cl, pH 8.2, containing 200 mM NaCl.

Storage: 4 °C,-20 °C

Storage Comment: Short Term Storage: +4°C
Long Term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C.

Expiry Date: 3 months

Target Details

Target: FABP4 (Fatty Acid Binding Protein 4, Adipocyte (FABP4))

Alternative Name: FABP4 (FABP4 Products)

Synonyms: A-FABP Protein, AFABP Protein, ALBP Protein, aP2 Protein, LOC100223994 Protein, FABP Protein, AP2 Protein, FABP3 Protein, FABP4 Protein, MGC84940 Protein, fabp4 Protein, 422/aP2 Protein, ALBP/Ap2 Protein, Ap2 Protein, Lbpl Protein, Albp Protein, fatty acid binding protein 4 Protein, fatty acid-binding protein, adipocyte Protein, fatty acid binding protein 4, adipocyte Protein, fatty acid binding protein 4, adipocyte L homeolog Protein, Fatty acid-binding protein, adipocyte Protein, adipocyte fatty acid-binding protein Protein, adipocyte fatty acid binding protein Protein, FABP4 Protein, LOC100223994 Protein, fabp4.L Protein, fabp4 Protein, Fabp4 Protein, LOC100732353 Protein, LOC100861279 Protein, LOC100057425 Protein, LOC395224 Protein

Background: FABP4 is a fatty acid binding protein in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs regulate the fatty acid uptake, transport, and metabolism. aP2, the mouse form of FABP4, seems to be central to the pathway that links obesity to insulin resistance. aP2 was shown to be an adipokine linking adipocytes to hepatic glucose production and that neutralizing secreted aP2 may represent an effective therapeutic strategy against diabetes.

Molecular Weight: ~16kDa (SDS-PAGE)

UniProt: P15090

Pathways: Brown Fat Cell Differentiation