TNFRSF18 Protein (AA 20-152) (Fc Tag)
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- Target See all TNFRSF18 Proteins
- TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-152
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TNFRSF18 protein is labelled with Fc Tag.
- Application
- SDS-PAGE (SDS)
- Specificity
- Binds to mouse GITRL.
- Cross-Reactivity
- Mouse (Murine)
- Characteristics
- Mouse GITR (aa 20-152) is fused at the C-terminus to the Fc portion of human IgG1.
- Purity
- >95 % (SDS-PAGE)
- Endotoxin Level
- <0.01EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product TNFRSF18 Protein
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Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 26-161) protein (His tag)
TNFRSF18 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 26-161) protein (Fc Tag)TNFRSF18 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 20-156) protein (His tag)TNFRSF18 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 26-161) protein (His-Avi Tag,Biotin)TNFRSF18 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 22-153) protein (His tag)TNFRSF18 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (Active) protein (His tag,Fc Tag)TNFRSF18 Origin: Mouse Host: Human Cells Recombinant > 90 % as determined by SDS-PAGE Active
Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) protein (mFc-His Tag)TNFRSF18 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. FACS
Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 1-241) protein (GST tag)TNFRSF18 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 26-115) protein (GST tag)TNFRSF18 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) protein (Fc-His Tag)TNFRSF18 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with 50 μL sterile water.
- Concentration
- Lot specific
- Buffer
- Lyophilized. Contains PBS.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. - Expiry Date
- 6 months
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- Target
- TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
- Alternative Name
- GITR (TNFRSF18 Products)
- Synonyms
- GITR Protein, TNFRSF18 Protein, AITR Protein, Gitr Protein, CD357 Protein, GITR-D Protein, TNF receptor superfamily member 18 Protein, tumor necrosis factor receptor superfamily, member 18 Protein, TNFRSF18 Protein, Tnfrsf18 Protein
- Background
- GITR (Glucocorticoid-induced TNF receptor) is the receptor for TNFSF18. It is involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T cell receptor-mediated cell death. GITR serves as a negative regulator for NK cell activation. It mediates NF-kappaB activation via the TRAF2/NIK pathway.
- Molecular Weight
- ~45kDa (SDS-PAGE)
- UniProt
- O35714
- Pathways
- Cancer Immune Checkpoints
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