Chloride Channel 5 Protein (CLCN5) (AA 1-746) (GST tag)

Catalog No. ABIN1776894

Product Details

Target: Chloride Channel 5 (CLCN5)

Protein Type: Recombinant

Protein Characteristics: AA 1-746

Origin: Human

Source: Wheat germ

Purification tag / Conjugate: This Chloride Channel 5 protein is labelled with GST tag.

Application: ELISA, Western Blotting (WB), Antibody Array (AA), Affinity Purification (AP)

Purpose: CLCN5 (Human) Recombinant Protein (P01)

Sequence: MDFLEEPIPG VGTYDDFNTI DWVREKSRDR DRHREITNKS KESTWALIHS VSDAFSGWLL MLLIGLLSGS LAGLIDISAH WMTDLKEGIC TGGFWFNHEH CCWNSEHVTF EERDKCPEWN SWSQLIISTD EGAFAYIVNY FMYVLWALLF AFLAVSLVKV FAPYACGSGI PEIKTILSGF IIRGYLGKWT LVIKTITLVL AVSSGLSLGK EGPLVHVACC CGNILCHCFN KYRKNEAKRR EVLSAAAAAG VSVAFGAPIG GVLFSLEEVS YYFPLKTLWR SFFAALVAAF TLRSINPFGN SRLVLFYVEF HTPWHLFELV PFILLGIFGG LWGALFIRTN IAWCRKRKTT QLGKYPVIEV LVVTAITAIL AFPNEYTRMS TSELISELFN DCGLLDSSKL CDYENRFNTS KGGELPDRPA GVGVYSAMWQ LALTLILKIV ITIFTFGMKI PSGLFIPSMA VGAIAGRLLG VGMEQLAYYH QEWTVFNSWC SQGADCITPG LYAMVGAAAC LGGVTRMTVS LVVIMFELTG GLEYIVPLMA AAMTSKWVAD ALGREGIYDA HIRLNGYPFL EAKEEFAHKT LAMDVMKPRR NDPLLTVLTQ DSMTVEDVET IISETTYSGF PVVVSRESQR LVGFVLRRDL IISIENARKK QDGVVSTSII YFTEHSPPLP PYTPPTLKLR NILDLSPFTV TDLTPMEIVV DIFRKLGLRQ CLVTHNGRLL GIITKKDVLK HIAQMANQDP DSILFN

Characteristics: Human CLCN5 full-length ORF ( NP_000075.1, 1 a.a. - 746 a.a.) recombinant protein with GST-tag at N-terminal.

Purification: in vitro wheat germ expression system

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

Restrictions: For Research Use only

Handling

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -80 °C

Storage Comment: Best use within three months from the date of receipt of this protein.

References

Hryciw, Jenkin, Simcocks, Grinfeld, McAinch, Poronnik: "The interaction between megalin and ClC-5 is scaffolded by the Na?-H? exchanger regulatory factor 2 (NHERF2) in proximal tubule cells." in: The international journal of biochemistry & cell biology, Vol. 44, Issue 5, pp. 815-23, (2012) (PubMed).

Target Details

Target: Chloride Channel 5 (CLCN5)

Alternative Name: CLCN5 (CLCN5 Products)

Synonyms: CLCN3 Protein, CLCN5 Protein, clcn5-A Protein, DKFZp469O2315 Protein, 5430408K11Rik Protein, ClC-5 Protein, Clc5 Protein, D930009B12Rik Protein, DXImx42e Protein, Sfc13 Protein, T25545 Protein, CLC5 Protein, CLCK2 Protein, DENTS Protein, NPHL1 Protein, NPHL2 Protein, XLRH Protein, XRN Protein, hCIC-K2 Protein, CLCN4 Protein, Clcn5 Protein, chloride voltage-gated channel 5 Protein, chloride channel, voltage-sensitive 5 L homeolog Protein, chloride channel, voltage-sensitive 5 Protein, CLCN5 Protein, clcn5.L Protein, clcn5 Protein, Clcn5 Protein

Background: Full Gene Name: chloride channel 5
Synonyms: CLC5,CLCK2,DENTS,NPHL1,NPHL2,XLRH,XRN,hCIC-K2,hClC-K2

Gene ID: 1184

NCBI Accession: NM_000084