ERCC2 Protein (AA 1-405) (GST tag)
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- Target See all ERCC2 Proteins
- ERCC2 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-405
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Origin
- Human
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Source
- Wheat germ
- Purification tag / Conjugate
- This ERCC2 protein is labelled with GST tag.
- Application
- Western Blotting (WB), ELISA, Antibody Array (AA), Affinity Purification (AP)
- Purpose
- ERCC2 (Human) Recombinant Protein (P01)
- Sequence
- MRELKRTLDA KGHGVLEMPS GTGKTVSLLA LIMAYQRAYP LEVTKLIYCS RTVPEIEKVI EELRKLLNFY EKQEGEKLPF LGLALSSRKN LCIHPEVTPL RFGKDVDGKC HSLTASYVRA QYQHDTSLPH CRFYEEFDAH GREVPLPAGI YNLDDLKALG RRQGWCPYFL ARYSILHANV VVYSYHYLLD PKIADLVSKE LARKAVVVFD EAHNIDNVCI DSMSVNLTRR TLDRCQGNLE TLQKTVLRIK ETDEQRLRDE YRRLVEGLRE ASAARETDAH LANPVLPDEV LQEAVPGSIR TAEHFLGFLR RLLEYVKWRL RVQHVVQESP PAFLSGLAQR VCIQRKPLRF CAERLRSLLH TLEITDLADF SPLTLLANFA TLVSTYAKGQ AQHCGSSRNQ KRSHP
- Characteristics
- Human ERCC2 full-length ORF ( AAH08346, 1 a.a. - 405 a.a.) recombinant protein with GST-tag at N-terminal.
- Purification
- in vitro wheat germ expression system
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
- Handling Advice
- Aliquot to avoid repeated freezing and thawing.
- Storage
- -80 °C
- Storage Comment
- Best use within three months from the date of receipt of this protein.
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Cadmium inhibits non-homologous end-joining and over-activates the MRE11-dependent repair pathway." in: Mutation research, Vol. 654, Issue 1, pp. 13-21, (2008) (PubMed).
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Cadmium inhibits non-homologous end-joining and over-activates the MRE11-dependent repair pathway." in: Mutation research, Vol. 654, Issue 1, pp. 13-21, (2008) (PubMed).
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- Target
- ERCC2 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2))
- Alternative Name
- ERCC2 (ERCC2 Products)
- Synonyms
- COFS2 Protein, EM9 Protein, TTD Protein, XPD Protein, AA407812 Protein, AU020867 Protein, AW240756 Protein, CXPD Protein, Ercc-2 Protein, MGC89573 Protein, CG9433 Protein, DhR3 Protein, DhXPD Protein, DmXPD Protein, Dmel\\CG9433 Protein, ERCC2 Protein, XPD/ERCC2 Protein, l(2)SH2 2137 Protein, l(2)SH2137 Protein, xpd Protein, zgc:56365 Protein, ERCC excision repair 2, TFIIH core complex helicase subunit Protein, excision repair cross-complementing rodent repair deficiency, complementation group 2 Protein, excision repair cross-complementation group 2 Protein, Xeroderma pigmentosum D Protein, ERCC2 Protein, Ercc2 Protein, ercc2 Protein, Xpd Protein
- Background
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Gene: excision repair cross-complementing rodent repair deficiency, complementation group 2
Synonyms: COFS2, EM9, MGC102762, MGC126218, MGC126219, TTD, XPD - Gene ID
- 2068
- Pathways
- DNA Damage Repair
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