M6PR Protein (AA 1-277, full length) (GST tag)

Catalog No. ABIN1608018

Product Details

Target: M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))

Protein Type: Recombinant

Protein Characteristics: AA 1-277, full length

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This M6PR protein is labelled with GST tag.

Application: ELISA

Sequence: MFPFYSCWRT GLLLLLLAVA VRESWQTEEK TCDLVGEKGK ESEKELALVK RLKPLFNKSF ESTVGQGSDT YIYIFRVCRE AGNHTSGAGL VQINKSNGKE TVVGRLNETH IFNGSNWIML IYKGGDEYDN HCGKEQRRAV VMISCNRHTL ADNFNPVSEE RGKVQDCFYL FEMDSSLACS PEISHLSVGS ILLVTFASLV AVYVVGGFLY QRLVVGAKGM EQFPHLAFWQ DLGNLVADGC DFVCRSKPRN VPAAYRGVGD DQLGEESEER DDHLLPM

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: 95 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C for extended storage, conserve at -20 °C or -80 °C

Target Details

Target: M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))

Alternative Name: Cation-dependent mannose-6-phosphate receptor protein (M6PR Products)

Synonyms: CD222 Protein, CIMPR Protein, M6P-R Protein, MPR1 Protein, MPRI Protein, CD-MPR Protein, MPR 46 Protein, MPR-46 Protein, MPR46 Protein, SMPR Protein, Mpr46 Protein, CDMPR Protein, m6pr Protein, MGC68896 Protein, MGC130765 Protein, zgc:77757 Protein, wu:fj81h11 Protein, MGC89423 Protein, M6PR Protein, mprd Protein, C16orf27 Protein, GNPTAG Protein, LP2537 Protein, RJD9 Protein, insulin like growth factor 2 receptor Protein, mannose-6-phosphate receptor, cation dependent Protein, mannose-6-phosphate receptor (cation dependent) L homeolog Protein, mannose-6-phosphate receptor (cation dependent) Protein, mannose-6-phosphate receptor (cation dependent) S homeolog Protein, Cation-dependent mannose-6-phosphate receptor Protein, N-acetylglucosamine-1-phosphate transferase gamma subunit Protein, IGF2R Protein, M6PR Protein, M6pr Protein, m6pr.L Protein, m6pr Protein, m6pr.S Protein, Ethha_1678 Protein, mprd Protein, GNPTG Protein

Background: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.

Molecular Weight: 58.4 kD

UniProt: P20645