HMGCS2 Protein (AA 38-508) (His tag)

Catalog No. ABIN1622498

Product Details

Target: HMGCS2 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))

Protein Type: Recombinant

Protein Characteristics: AA 38-508

Origin: Cow

Source: Yeast

Purification tag / Conjugate: This HMGCS2 protein is labelled with His tag.

Application: ELISA

Sequence: TVP AVPLAKTDTW PKDVGILAME VYFPAQYVDQ TELEKFNKVE AGRYTVGLGQ TQMGFCSVQE DVNSLCLTVV QQLMERTQLP WDSVGRLEVG TETIIDKSKA VKTVLMELFQ DSGNTDIEGI DTTNACYGGT ASLFNAANWM ESSSWDGRYA LVVCGDIAVY PSGNARPTGG AGAVAMLVGP EAPLVLERGL RGTHMENVYD FYKPDVTSEY PLVDGKLSIQ CYLRALDKCY AFYRQKIEKQ WKQAGIDRPF TLDDVQYMIF HTPFCKLVQK SLARLMFNDF LLASGDTQTG IYKGLEAFRG LKLEDTYTNK DVDKAFLKAS LNMFNKKTKN SLYLSTYNGN MYTSSLYGCL ASLLAHHSAQ DLAGSRIGAF SYGSGLAASF FSFRVSQDAS PGSPLEKLVS STSDLQKRLA SRKRVSPEEF TEIMNQREQY YHKMNFSPPG DKNSLFPGTW YLERVDELYR RKYARRPV

Specificity: Bos taurus (Bovine)

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: > 90 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C, for extended storage, conserve at -20 °C or -80 °C.

Target Details

Target: HMGCS2 (3-Hydroxy-3-Methylglutaryl-CoA Synthase 2 (Mitochondrial) (HMGCS2))

Alternative Name: Hydroxymethylglutaryl-CoA synthase, mitochondrial (HMGCS2) (HMGCS2 Products)

Synonyms: 1300002P16 Protein, mHS Protein, DDBDRAFT_0219349 Protein, DDBDRAFT_0219924 Protein, DDB_0219349 Protein, DDB_0219924 Protein, Hmgcs1 Protein, Mt3h3mg Protein, hmgCoA Protein, 3-hydroxy-3-methylglutaryl-CoA synthase 2 Protein, 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 Protein, hydroxymethylglutaryl-CoA synthase Protein, hydroxymethylglutaryl-coa synthase Protein, 3-HYDROXY-3-METHYLGLUTARYL-CoA SYNTHASE 2 Protein, HMGCS2 Protein, Hmgcs2 Protein, mvaS Protein, CNC05080 Protein, HMCS1 Protein, hgsA Protein, MFER_RS00425 Protein, LOC100285783 Protein, ECU10_0510 Protein, Eint_100450 Protein

Background: Recommended name: Hydroxymethylglutaryl-CoA synthase, mitochondrial.
Short name= HMG-CoA synthase.
EC= 2.3.3.10.
Alternative name(s): 3-hydroxy-3-methylglutaryl coenzyme A synthase

UniProt: Q2KIE6

Pathways: Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha