CYP11B1 Protein (AA 25-500) (His tag)

Catalog No. ABIN1634454

Product Details

Target: CYP11B1 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 1 (CYP11B1))

Protein Type: Recombinant

Protein Characteristics: AA 25-500

Origin: Guinea Pig

Source: Yeast

Purification tag / Conjugate: This CYP11B1 protein is labelled with His tag.

Application: ELISA

Sequence: GTRAVT ASKASVLPFE VIPQHQGNKR QRVLQFWKEQ NHDDLHLEMH QTFQELGPIF RCDVGSTRIV AVMLPEDCAR LHQAESPYPH RMHLEPWMAY REHRRQNLGV FLLNGPEWLS NRRWLNPNVL SPKAVQNLLP MVDTVARDFS EALKQKVLQS AQGSLTMDMQ PDIHKYTVEV SNFALFGERL GLFGCNPSSQ SLKFIHALEA VFKTTTQLMF LPRSLSRWMR SQAWKEHFEA WDYISEYAEN RIQKKYEELA RGCSQYNSIV ANLMLQGNLP LRAMKANIMD LVAGSVDTTA LPLMMTLFEL ARNPTVQQAL RQESMATEPN IYENPQRLRM ELPLLWAAIK ETLRMYPVGL FLERFLTSPL VLQNYHIPAG TLVHLNLYSM GRNPEVFLSP EHYNPQRWLE NKETYKHLAF GFGVRQCIGR RLAEVEMLLF LHHVLKSFCV ETAFQEDVKF AYRFVMMPTS APLLTFRPVS

Specificity: Cavia porcellus (Guinea pig)

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: > 90 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C, for extended storage, conserve at -20 °C or -80 °C.

Target Details

Target: CYP11B1 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 1 (CYP11B1))

Alternative Name: Cytochrome P450 11B1, mitochondrial (CYP11B1) (CYP11B1 Products)

Synonyms: CPN1 Protein, CYP11B Protein, FHI Protein, P450C11 Protein, AA389061 Protein, Cyp11b Protein, Cyp11b-1 Protein, Cp11ba Protein, RATCP11BA Protein, P450c11 Protein, cytochrome P450, family 11, subfamily B, polypeptide 1 Protein, cytochrome P450 family 11 subfamily B member 1 Protein, cytochrome P450, family 11, subfamily b, polypeptide 1 Protein, cytochrome P450, subfamily XI B, polypeptide 1 Protein, CYP11B1 Protein, Cyp11b1 Protein

Background: Recommended name: Cytochrome P450 11B1, mitochondrial.
Alternative name(s): Aldosterone synthase CYPXIB1 Cytochrome P450C11 Steroid 11-beta-hydroxylase.
EC= 1.14.15.4

UniProt: Q64408

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis