ATIC Protein (AA 1-499) (His tag)

Catalog No. ABIN1645126

Product Details

Target: ATIC (5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC))

Protein Type: Recombinant

Protein Characteristics: AA 1-499

Origin: Clostridium

Source: Yeast

Purification tag / Conjugate: This ATIC protein is labelled with His tag.

Application: ELISA

Sequence: MIKRALISVF NKNGILKLAK FLNEKGVEIL STGGTYKHLK ENGIPVIEVS EVTGFDEILD GRVKTLHPKI HGGILAIRDN KEHMDTIKNK GITPIDMVVV NLYPFFDKVK ENISFEEKVE FIDIGGPTMI RAAAKNFQDV VVLTDVNDYD DVIDQIEKTG EVAYNTKKRL AGKVFNLMSA YDGAISRFLL EDEYPEYLAV PYKKKMDLRY GENPHQTAAF YEAAFGDGAM KGFEQLNGKE LSYNNIKDMD IAWKVVNEFD ETVCCALKHN SPCGVAIGEN PLDAYKKAFE CDDTSIFGGI VALNKVIDKP AAEEMVKIFL EIVIAPDFTA DALEVLKSKK NLRVIKANEK PSDNFELAKV DGAMLVQSAD NKLTEKMEVV TDKKPTDEEM RDMIFGMKVV KYVKSNAIVV VKNGAAVGIG GGQVNRIWPA KDAMERGKGA AVLASDAFFP FGDIVEEAHK NGIKAIIQPG GSIRDQESID GCNKYGISMV MTGIRHFKH

Specificity: Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: > 90 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C, for extended storage, conserve at -20 °C or -80 °C.

Target Details

Target: ATIC (5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC))

Alternative Name: Bifunctional purine biosynthesis protein PurH (purH) (ATIC Products)

Synonyms: AICAR Protein, AICARFT Protein, IMPCHASE Protein, PURH Protein, purH Protein, 2610509C24Rik Protein, AA536954 Protein, AW212393 Protein, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase L homeolog Protein, bifunctional purine biosynthesis protein PurH Protein, bifunctional purine biosynthesis protein purH Protein, Bifunctional purine biosynthesis protein purH Protein, Bifunctional purine biosynthesis protein PurH Protein, 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase Protein, atic.L Protein, purH Protein, ATIC Protein, Atic Protein

Background: Recommended name: Bifunctional purine biosynthesis protein PurH Including the following 2 domains: Phosphoribosylaminoimidazolecarboxamide formyltransferase.
EC= 2.1.2.3.
Alternative name(s): AICAR transformylase IMP cyclohydrolase.
EC= 3.5.4.10.
Alternative name(s): ATIC IMP synthase Inosinicase

UniProt: Q97J91