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IL17RC Protein (C-Term, Extracellular Domain)

IL17RC Origin: Human Host: HEK-293T Cells Recombinant > 98 %, as determined by SDS-PAGE and HPLC
Catalog No. ABIN1684628
  • Target See all IL17RC Proteins
    IL17RC (Interleukin 17 Receptor C (IL17RC))
    Protein Type
    Recombinant
    Protein Characteristics
    C-Term, Extracellular Domain
    Origin
    • 12
    • 4
    Human
    Source
    • 6
    • 5
    • 3
    • 1
    • 1
    HEK-293T Cells
    Specificity
    Optimized DNA sequence encoding extracellular domain of human IL-17RC receptor including a C terminal Human IgG1 Fc tag was expressed in HEK293 cells.
    Characteristics
    Recombinant IL17RC-Fc is a homodimer protein consisting of 675 amino acid residue subunits, due to glycosylation migrates as an approximately 100kD protein under reducing SDS-PAGE conditions.
    Purity
    > 98 %, as determined by SDS-PAGE and HPLC
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
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  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS solution, pH7.2
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    The lyophilized protein is stable for at least years from date of receipt at -20 °C. Upon reconstitution, this cytokine can be stored in working aliquots at - 8 °C for one month, or at -20 °C for six months, with a carrier protein without detectable loss of activity.
    Expiry Date
    12-24 months
  • Target
    IL17RC (Interleukin 17 Receptor C (IL17RC))
    Alternative Name
    IL17RC (IL17RC Products)
    Synonyms
    IL17-RL Protein, IL17RL Protein, 1110025H02Rik Protein, Gm19850 Protein, IL-17RC Protein, IL17-RC Protein, Il17rl Protein, interleukin 17 receptor C Protein, Il17rc Protein, IL17RC Protein
    Background
    Common gamma chain Interleukin (IL)-2, IL-4, IL-7, IL-9 and IL-15 belong to a family of cytokines whose receptors share the common gamma chain (gamma c). Despite some redundancy, thesecytokines that signal through the gamma c (gamma c cytokines) have essentially distinct and oftencritical effects in normal T-cell development, survival, proliferation and differentiation. Importantly, they have also been implicated,directly or indirectly, in T-cell leukemogenesis.
    UniProt
    Q8NAC3
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