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Proteoglycan 3 Protein (PRG3) (AA 18-225) (His tag)

PRG3 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1691332
  • Target See all Proteoglycan 3 (PRG3) Proteins
    Proteoglycan 3 (PRG3)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 18-225
    Origin
    • 4
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    Human Cells
    Purification tag / Conjugate
    This Proteoglycan 3 protein is labelled with His tag.
    Purpose
    Recombinant Human Proteoglycan 3/PRG3 (C-6His)
    Sequence
    LHLENDAPHL ESLETQADLG QDLDSSKEQE RDLALTEEVI QAEGEEVKAS ACQDNFEDEE AMESDPAALD KDFQCPREED IVEVQGSPRC KTCRYLLVRT PKTFAEAQNV CSRCYGGNLV SIHDFNFNYR IQCCTSTVNQ AQVWIGGNLR GWFLWKRFCW TDGSHWNFAY WSPGQPGNGQ GSCVALCTKG GYWRRAQCDK QLPFVCSFVD HHHHHH
    Characteristics
    Recombinant Human Proteoglycan 3/PRG3 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Leu18-Phe225) of Human PRG3 fused with a polyhistidine tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product PRG3 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.2.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    4 °C/-20 °C/-80 °C
    Storage Comment
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    3 months
  • Target
    Proteoglycan 3 (PRG3)
    Alternative Name
    Proteoglycan-3 (PRG3 Products)
    Synonyms
    MBP2 Protein, MBPH Protein, proteoglycan 3, pro eosinophil major basic protein 2 Protein, proteoglycan 3 Protein, PRG3 Protein, Prg3 Protein
    Sub Type
    Fusionprotein
    Background
    Proteoglycan 3, also known as Eosinophil major basic protein homolog, Prepro-major basic protein homolog, PRG3 and MBPH, contains one C-type lectin domain. Proteoglycans are a major component of the animal extracellular matrix. PRG3 localizes to the eosinophil secondary granule and is expressed in bone marrow, not detected in placenta. PRG3 has similar cytotoxic and cytostimulatory activities to PRG2/MBP. In vitro, PRG3 can stimulate neutrophil superoxide production and IL8 release, histamine and leukotriene C4 release from basophils.
    Alternative Names: Proteoglycan 3, Eosinophil Major Basic Protein Homolog, Prepro-Major Basic Protein Homolog, Prepro-MBPH, PRG3, MBPH
    Molecular Weight
    24.6 kDa
    UniProt
    Q9Y2Y8
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