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APOA4 Protein (AA 21-396) (His tag)

APOA4 Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1691363
  • Target See all APOA4 Proteins
    APOA4 (Apolipoprotein A-IV (APOA4))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 21-396
    Origin
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Source
    • 12
    • 6
    • 1
    • 1
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This APOA4 protein is labelled with His tag.
    Purpose
    Recombinant Human Apolipoprotein A-IV/ApoA4 (C-6His)
    Sequence
    EVSADQVATV MWDYFSQLSN NAKEAVEHLQ KSELTQQLNA LFQDKLGEVN TYAGDLQKKL VPFATELHER LAKDSEKLKE EIGKELEELR ARLLPHANEV SQKIGDNLRE LQQRLEPYAD QLRTQVNTQA EQLRRQLTPY AQRMERVLRE NADSLQASLR PHADELKAKI DQNVEELKGR LTPYADEFKV KIDQTVEELR RSLAPYAQDT QEKLNHQLEG LTFQMKKNAE ELKARISASA EELRQRLAPL AEDVRGNLRG NTEGLQKSLA ELGGHLDQQV EEFRRRVEPY GENFNKALVQ QMEQLRQKLG PHAGDVEGHL SFLEKDLRDK VNSFFSTFKE KESQDKTLSL PELEQQQEQQ QEQQQEQVQM LAPLESVDHH HHHH
    Characteristics
    Recombinant Human Apolipoprotein A4/APOA4 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Glu21-Ser396) of Human APOA4 fused with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product APOA4 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    4 °C/-20 °C/-80 °C
    Storage Comment
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    3 months
  • Target
    APOA4 (Apolipoprotein A-IV (APOA4))
    Alternative Name
    Apolipoprotein-A-IV (APOA4 Products)
    Synonyms
    Apo-AIV Protein, ApoA-IV Protein, apoAIV Protein, APOAIV Protein, APOA4 Protein, myh11 Protein, Apoa-4 Protein, apolipoprotein A4 Protein, apolipoprotein A4 L homeolog Protein, apolipoprotein A-IV Protein, apolipoprotein A-IV a Protein, APOA4 Protein, Apoa4 Protein, apoa4 Protein, apoa4.L Protein, apoa4a Protein
    Sub Type
    Fusionprotein
    Background
    Apolipoprotein A4 (APOA4) is a secreted protein that belongs to the apolipoprotein A1/A4/E family. Apoa-IV is a major component of HDL and chylomicrons. APOA4 is secreted into circulation on the surface of newly synthesized chylomicron particles. APOA4 play a role in the regulation of appetite and satiety in rodent models. APOA4 involved in chylomicrons and VLDL secretion and catabolism and required for efficient activation of lipoprotein lipase by ApoC-II. In addition, APOA4 is a potent activator of lecithin-cholesterol acyltransferase in vitro.
    Alternative Names: Apolipoprotein A-IV, Apo-AIV, ApoA-IV, Apolipoprotein A4, APOA4
    Molecular Weight
    44.44 kDa
    UniProt
    P06727
    Pathways
    Lipid Metabolism
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