Syntaxin 6 Protein (STX6) (AA 2-234)

Catalog No. ABIN1691989

Product Details

Target: Syntaxin 6 (STX6)

Protein Type: Recombinant

Protein Characteristics: AA 2-234

Origin: Human

Source: Escherichia coli (E. coli)

Purpose: Recombinant Human Syntaxin-6/STX6

Sequence: SMEDPFFVVK GEVQKAVNTA QGLFQRWTEL LQDPSTATRE EIDWTTNELR NNLRSIEWDL EDLDETISIV EANPRKFNLD ATELSIRKAF ITSTRQVVRD MKDQMSTSSV QALAERKNRQ ALLGDSGSQN WSTGTTDKYG RLDRELQRAN SHFIEEQQAQ QQLIVEQQDE QLELVSGSIG VLKNMSQRIG GELEEQAVML EDFSHELEST QSRLDNVMKK LAKVSHMTSD RRQ

Characteristics: Recombinant Human Syntaxin-6/STX6 is produced with our E. coli expression system. The target protein is expressed with sequence (Ser2-Gln234) of Human STX6.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: Syntaxin 6 (STX6)

Alternative Name: STX6 (STX6 Products)

Synonyms: CG7736 Protein, CT23545 Protein, Dm Syx6 Protein, DmSyx6 Protein, Dmel\\CG7736 Protein, SYN6 Protein, SYX6/10 Protein, Syx Protein, MGC78971 Protein, MGC132090 Protein, STX6 Protein, fb51b08 Protein, wu:fb51b08 Protein, zgc:110658 Protein, si:dkey-121a11.2 Protein, LOC734102 Protein, Syx6 Protein, Bmsyx6 Protein, Syntaxin-6 Protein, 2310039E05Rik Protein, 2410005I16Rik Protein, AA437559 Protein, AI415714 Protein, AI845861 Protein, Syntaxin 6 Protein, syntaxin 6 L homeolog Protein, syntaxin 6 Protein, Syx6 Protein, stx6.L Protein, STX6 Protein, stx6 Protein, Stx6 Protein

Background: Syntaxin-6 (STX6) is a single-pass type IV membrane protein, which belongs to the Syntaxin family. STX6 is mainly localized in the plasma membrane. STX6 contains one t-SNARE coiled-coil homology domain and involved in intracellular vesicle trafficking. When STX6 function is inhibited, internalization through caveolae is dramaticaliy reduced, whereas other endocytic mechanisms are unaffected. It is reported that STX6 is necessary for proper expression of focal adhesion kinase and integrin alpha5 adhesion receptor.
Alternative Names: Syntaxin-6, STX6

Molecular Weight: 26.8 kDa

UniProt: O43752

Pathways: Synaptic Vesicle Exocytosis