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Iba1 Protein (AA 2-147) (His tag)

IBA1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1692029
  • Target See all Iba1 (IBA1) Proteins
    Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 2-147
    Origin
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 11
    • 5
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This Iba1 protein is labelled with His tag.
    Purpose
    Recombinant Human Allograft Inflammatory Factor 1/AIF1 (C-6His)
    Sequence
    SQTRDLQGGK AFGLLKAQQE ERLDEINKQF LDDPKYSSDE DLPSKLEGFK EKYMEFDLNG NGDIDIMSLK RMLEKLGVPK THLELKKLIG EVSSGSGETF SYPDFLRMML GKRSAILKMI LMYEEKAREK EKPTGPPAKK AISELPLEHH HHHH
    Characteristics
    Recombinant Human Allograft Inflammatory Factor 1/AIF1 is produced with our E. coli expression system. The target protein is expressed with sequence (Ser2-Pro147) of Human AIF1 fused with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product IBA1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    4 °C/-20 °C/-80 °C
    Storage Comment
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    3 months
  • Target
    Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))
    Alternative Name
    AIF1 (IBA1 Products)
    Synonyms
    AIF-1 Protein, IBA1 Protein, IRT-1 Protein, IRT1 Protein, AI607846 Protein, D17H6S50E Protein, G1 Protein, Iba1 Protein, Bart1 Protein, iba1 Protein, mrf-1 Protein, fa04b11 Protein, wu:fa04b11 Protein, AIF Protein, AIF1 Protein, aif1 Protein, allograft inflammatory factor 1 Protein, AIF1 Protein, Aif1 Protein, aif1 Protein
    Sub Type
    Fusionprotein
    Background
    Allograft Inflammatory Factor 1 (AIF1) contains two EF-hand domains and exists as a homodimer. AIF1 can be detected in T-lymphocytes and peripheral blood mononuclear cells. AIF1 functions as actin-binding protein that enhances membrane ruffling and RAC activation and can enhance the actin-bundling activity of LCP1. In addition, AIF1 plays a role in RAC signaling and in phagocytosis and may also in macrophage activation and function. AIF1 promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes and plays a role in vascular inflammation.
    Alternative Names: Allograft Inflammatory Factor 1, AIF-1, Ionized Calcium-Binding Adapter Molecule 1, Protein G1, AIF1, G1, IBA1
    Molecular Weight
    17.7 kDa
    UniProt
    P55008
    Pathways
    Smooth Muscle Cell Migration
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