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CCL18 Protein (AA 21-89) (His tag)

CCL18 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1692045
  • Target See all CCL18 Proteins
    CCL18 (Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 21-89
    Origin
    • 13
    • 1
    Human
    Source
    • 8
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This CCL18 protein is labelled with His tag.
    Purpose
    Recombinant Human C-C Motif Chemokine 18/CCL18/PARC (N-6His)
    Sequence
    MGSSHHHHHH SSGLVPRGSH MAQVGTNKEL CCLVYTSWQI PQKFIVDYSE TSPQCPKPGV ILLTKRGRQI CADPNKKWVQ KYISDLKLNA
    Characteristics

    Recombinant Human C-C Motif Chemokine 18/CCL18/PARC (N-6His)

    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product CCL18 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    4 °C/-20 °C/-80 °C
    Storage Comment
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CCL18 (Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18))
    Alternative Name
    C-C Motif Chemokine 18/CCL18 (CCL18 Products)
    Synonyms
    H7AP1 Protein, PARC Protein, RP3-330M21.2 Protein, AMAC-1 Protein, AMAC1 Protein, CKb7 Protein, DC-CK1 Protein, DCCK1 Protein, MIP-4 Protein, SCYA18 Protein, cullin 9 Protein, C-C motif chemokine ligand 18 Protein, CUL9 Protein, CCL18 Protein
    Background
    Recombinant Human C-C Motif Chemokine 18/CCL18 is produced with our E. coli expression system. The target protein is expressed with sequence (Ala21-Ala89) of Human CCL18 fused with a 6His tag at the N-terminus.
    C-C Motif Chemokine 18 (CCL18) is secreted protein that belongs to the intercrine β (chemokine CC) family. CCL18 is expressed at high levels in the lung, lymph nodes, placenta, bone marrow, and dendritic cells. CCL18 is a chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. CCL18 may be involved in B-cell migration into B-cell follicles in lymph nodes. CCL18 attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses.
    Molecular Weight
    10.1 kDa
    UniProt
    P55774
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