ETS1 Protein (AA 1-272) (His tag)

Catalog No. ABIN1692093

Product Details

Target: ETS1 (V-Ets erythroblastosis Virus E26 Oncogene Homolog 1 (Avian) (ETS1))

Protein Type: Recombinant

Protein Characteristics: AA 1-272

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This ETS1 protein is labelled with His tag.

Purpose: Recombinant Human ETS1/EWSR2/P54 (N-6His)

Sequence: MGSSHHHHHH SSGLVPRGSH MKAAVDLKPT LTIIKTEKVD LELFPSPDME CADVPLLTPS SKEMMSQALK ATFSGFTKEQ QRLGIPKDPR QWTETHVRDW VMWAVNEFSL KGVDFQKFCM NGAALCALGK DCFLELAPDF VGDILWEHLE ILQKEDVKPY QVNGVNPAYP ESRYTSDYFI SYGIEHAQCV PPSEFSEPSF ITESYQTLHP ISSEELLSLK YENDYPSVIL RDPLQTDTLQ NDYFAIKQEV VTPDNMCMGR TSRGKLGGQD SFESIESYDS CGQEMGKEEK QT

Characteristics: Recombinant Human ETS1 Protein/ETS1 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Thr272) of Human ETS1 fused with a 6His tag at the N-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl,1 mM EDTA, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: ETS1 (V-Ets erythroblastosis Virus E26 Oncogene Homolog 1 (Avian) (ETS1))

Alternative Name: ETS1 (ETS1 Products)

Synonyms: ETS-1 Protein, EWSR2 Protein, ets1a-a Protein, XE1-a Protein, X1-c-ets-1a Protein, ETS-1A Protein, ETS-1B Protein, TNIP1 Protein, c-ets-1 Protein, c-ets1 Protein, Ets-1 Protein, Etsoncb Protein, Tpl1 Protein, ets1 Protein, ets Protein, AI196000 Protein, AI448617 Protein, D230050P06 Protein, cb516 Protein, id:ibd1116 Protein, zgc:110573 Protein, XE1-b Protein, ets-1 Protein, ets1-B Protein, ETS proto-oncogene 1, transcription factor Protein, v-ets avian erythroblastosis virus E26 oncogene homolog 1 S homeolog Protein, v-ets avian erythroblastosis virus E26 oncogene homolog 1 Protein, v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) Protein, E26 avian leukemia oncogene 1, 5' domain Protein, v-ets avian erythroblastosis virus E26 oncogene homolog 1 L homeolog Protein, ETS1 Protein, ets1.S Protein, Ets1 Protein, ets1 Protein, ets1.L Protein

Sub Type: Fusionprotein

Background: ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or repressors of numerous genes. They are involved in stem cell development, cell senescence and death, and tumorigenesis. ETS1 is a transcription factor, containing one ETS DNA-binding domain and one PNT (pointed) domain. it has been shown to interact with TTRAP, UBE2I and Death Associated Protein 6.
Alternative Names: ETS1 Protein, Protein C-ets-1, V-ets Erythroblastosis Virus E26 Oncogene Homolog 1 (Avian), Isoform CRA_a, ETS1, hCG_1732038

Molecular Weight: 33 kDa

UniProt: Q96AC5