PDCD4 Protein (AA 212-357) (His tag)
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- Target See all PDCD4 Proteins
- PDCD4 (Programmed Cell Death 4 (PDCD4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 212-357
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PDCD4 protein is labelled with His tag.
- Purpose
- Recombinant Human PDCD4/H731 (C-6His)
- Sequence
- MKASHREMTS KLLSDLCGTV MSTTDVEKSF DKLLKDLPEL ALDTPRAPQL VGQFIARAVG DGILCNTYID SYKGTVDCVQ ARAALDKATV LLSMSKGGKR KDSVWGSGGG QQSVNHLVKE IDMLLKEYLL SGDISEAEHC LKELEVPLEH HHHHH
- Characteristics
- Recombinant Human Programmed Cell Death Protein 4/PDCD4 is produced with our E. coli expression system. The target protein is expressed with sequence (Lys212-Pro357) of Human PDCD4 fused with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product PDCD4 Protein
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Programmed Cell Death 4 (PDCD4) (AA 212-357) protein (His tag)
PDCD4 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Programmed Cell Death 4 (PDCD4) (AA 1-469) protein (GST tag)PDCD4 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Programmed Cell Death 4 (PDCD4) (AA 1-469) protein (Strep Tag)Crystallography grade PDCD4 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Programmed Cell Death 4 (PDCD4) (AA 1-469) protein (Strep Tag)Crystallography grade PDCD4 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - Expiry Date
- 3 months
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- Target
- PDCD4 (Programmed Cell Death 4 (PDCD4))
- Alternative Name
- PDCD4 (PDCD4 Products)
- Synonyms
- H731 Protein, D19Ucla1 Protein, Ma3 Protein, Tis Protein, Dug Protein, cb45 Protein, pdcd4 Protein, sb:cb45 Protein, wu:fc84b08 Protein, h731 Protein, MGC69337 Protein, PDCD4 Protein, wu:fa55g03 Protein, wu:fb08a11 Protein, wu:fe01a02 Protein, zgc:66311 Protein, programmed cell death 4 Protein, programmed cell death 4b Protein, programmed cell death 4 L homeolog Protein, programmed cell death 4 (neoplastic transformation inhibitor) Protein, programmed cell death 4a Protein, PDCD4 Protein, Pdcd4 Protein, pdcd4b Protein, pdcd4.L Protein, pdcd4 Protein, pdcd4a Protein
- Sub Type
- Fusionprotein
- Background
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Programmed Cell Death Protein 4 (PDCD4) is a member of the PDCD4 family. PDCD4 and EIF4A1 form a heterotrimer. One molecule of PDCD4 binds two molecules of EIF4A1. PDCD4 takes part in apoptosis via inhibiting translation initiation and cap-dependent translation.PDCD4 promotes colonic neoplastic transformation and tumor invasion. PDCD4 is an important target for microrna R-21 in breast cancer cells. Shortage of PDCD4 expression is associated with colorectal cancer. Overexpression of PDCD4 in carcinoid cells results in inhibition of cell proliferation.
Alternative Names: Programmed Cell Death Protein 4, Neoplastic Transformation Inhibitor Protein, Nuclear Antigen H731-Like, Protein 197/15a, PDCD4, H731 - Molecular Weight
- 17 kDa
- UniProt
- Q53EL6
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