alpha Taxilin Protein (AA 1-162) (His tag)
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- Target See all alpha Taxilin (TXLNA) Proteins
- alpha Taxilin (TXLNA) (Taxilin alpha (TXLNA))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-162
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This alpha Taxilin protein is labelled with His tag.
- Purpose
- Recombinant Human α-Taxilin/TXLNA (N, C-6His)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MKNQDKKNGA AKQSNPKSSP GQPEAGPEGA QERPSQAAPA VEAEGPGSSQ APRKPEGAQA RTAQSGALRD VSEELSRQLE DILSTYCVDN NQGGPGEDGA QGEPAEPEDA EKSRTYVARN GEPEPTPVVN GEKEPSKGDP NTEEIRQSDE VGDRDHRRPQ EKLEHHHHHH
- Characteristics
- Recombinant Human alpha-Taxilin is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Lys162) of Human alpha-taxilin fused with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product TXLNA Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - Expiry Date
- 4 months
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- Target
- alpha Taxilin (TXLNA) (Taxilin alpha (TXLNA))
- Alternative Name
- alpha taxilin (TXLNA Products)
- Synonyms
- fc21b12 Protein, im:7039434 Protein, wu:fc21b12 Protein, zgc:162882 Protein, TXLNA Protein, txlnb Protein, MGC154810 Protein, 2600010N21Rik Protein, AI425952 Protein, AW209241 Protein, Il14 Protein, Txln Protein, IL14 Protein, RP4-622L5.4 Protein, TXLN Protein, taxilin alpha Protein, taxilin alpha S homeolog Protein, txlna Protein, TXLNA Protein, txlna.S Protein, MCYG_06155 Protein, Txlna Protein
- Sub Type
- Fusionprotein
- Background
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Alpha-Taxilin belongs to the taxilin family. alpha-Taxilin exists in almost all tissues, with higher expression levels observed in the heart, kidney, liver, and pancreas. alpha-Taxilin binds to the C-terminal coiled coil region of syntaxin family members STX1A, STX3A, and STX4A, but not when these proteins are complexed with SNAP25, VAMP2 or STXBP1, suggesting that it interacts with syntaxins that do not form the SNARE complex. It is shown that alpha-Taxilin plays multiple roles in the generation and maintenance of neurons through modulation of the NAC-mediated translational machinary and/or the syntaxin-mediated vesicle traffic in the soma. In addition, alpha-Taxilin may be involved in intracellular vesicle traffic and potentially in calcium-dependent exocytosis in neuroendocrine cells.
Alternative Names: Alpha-Taxilin, TXLNA, TXLN - Molecular Weight
- 20.4 kDa
- UniProt
- P40222
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