SDCBP Protein (AA 2-298) (His tag)

Catalog No. ABIN1692393

Product Details

Target: SDCBP (Syndecan Binding Protein (Syntenin) (SDCBP))

Protein Type: Recombinant

Protein Characteristics: AA 2-298

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This SDCBP protein is labelled with His tag.

Purpose: Recombinant Human Syntenin-1/SDCBP/SYCL/MDA9 (C-6His)

Sequence: SLYPSLEDLK VDKVIQAQTA FSANPANPAI LSEASAPIPH DGNLYPRLYP ELSQYMGLSL NEEEIRANVA VVSGAPLQGQ LVARPSSINY MVAPVTGNDV GIRRAEIKQG IREVILCKDQ DGKIGLRLKS IDNGIFVQLV QANSPASLVG LRFGDQVLQI NGENCAGWSS DKAHKVLKQA FGEKITMTIR DRPFERTITM HKDSTGHVGF IFKNGKITSI VKDSSAARNG LLTEHNICEI NGQNVIGLKD SQIADILSTS GTVVTITIMP AFIFEHIIKR MAPSIMKSLM DHTIPEVLEH HHHHH

Characteristics: Recombinant Human Syntenin-1/SDCBP/SYCL/MDA9 is produced with our E. coli expression system. The target protein is expressed with sequence (Ser2-Val298) of Human SDCBP/Syntenin-1 fused with a 6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: -80 °C

Storage Comment: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: SDCBP (Syndecan Binding Protein (Syntenin) (SDCBP))

Alternative Name: Syntenin-1 (SDCBP Products)

Synonyms: MDA-9 Protein, ST1 Protein, SYCL Protein, TACIP18 Protein, Sycl Protein, syntenin-1 Protein, mda-9 Protein, st1 Protein, sycl Protein, tacip18 Protein, MGC81274 Protein, syntenin Protein, wu:fc51c03 Protein, wu:fk31e01 Protein, zgc:55679 Protein, zgc:77716 Protein, sb:eu862 Protein, si:dkey-235k4.1 Protein, syndecan binding protein Protein, syndecan binding protein L homeolog Protein, syndecan binding protein (syntenin) 2 Protein, syndecan binding protein (syntenin) Protein, SDCBP Protein, Sdcbp Protein, sdcbp.L Protein, LOC732879 Protein, sdcbp2 Protein, sdcbp Protein

Sub Type: Fusionprotein

Background: Syntenin-1 is a molecule linking syndecan-mediated signaling to the cytoskeleton. Syntenin-1 is primarily localized to membrane-associated adherens junctions and focal adhesions but also found at the endoplasmic reticulum and nucleus. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. Syntenin-1 may affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. It seems to function as an adapter protein, in adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Syntenin-1 seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA) and play a role in vesicular trafficking.
Alternative Names: \Syntenin-1, Melanoma differentiation-associated protein 9, Pro-TGF-alpha cytoplasmic domain-interacting protein 18, Scaffold protein Pbp1,Syndecan-binding protein 1, SDCBP, MDA9, SYCL,\""

Molecular Weight: 33.5 kDa

UniProt: O00560