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EGR1 Protein (AA 282-433) (His tag)

EGR1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1692429
  • Target See all EGR1 Proteins
    EGR1 (Early Growth Response 1 (EGR1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 282-433
    Origin
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 7
    • 4
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This EGR1 protein is labelled with His tag.
    Purpose
    Recombinant Human Early Growth Response Protein 1/EGR1/ZNF225 (N-6His)
    Sequence
    MGSSHHHHHH SSGLVPRGSH MQQPSLTPLS TIKAFATQSG SQDLKALNTS YQSQLIKPSR MRKYPNRPSK TPPHERPYAC PVESCDRRFS RSDELTRHIR IHTGQKPFQC RICMRNFSRS DHLTTHIRTH TGEKPFACDI CGRKFARSDE RKRHTKIHLR QKDKKADKSV VAS
    Characteristics
    Recombinant Human Early growth response protein 1/EGR1 is produced with our E. coli expression system. The target protein is expressed with sequence (Gln282-Ser433) of Human EGR1 fused with a 6His tag at the N-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product EGR1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    4 °C/-20 °C/-80 °C
    Storage Comment
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    5 months
  • Target
    EGR1 (Early Growth Response 1 (EGR1))
    Alternative Name
    EGR1 (EGR1 Products)
    Synonyms
    AT225 Protein, G0S30 Protein, KROX-24 Protein, NGFI-A Protein, TIS8 Protein, ZIF-268 Protein, ZNF225 Protein, A530045N19Rik Protein, ETR103 Protein, Egr-1 Protein, Krox-1 Protein, Krox-24 Protein, Krox24 Protein, NGF1-A Protein, NGFIA Protein, Zenk Protein, Zfp-6 Protein, Zif268 Protein, egr Protein, Ngf1 Protein, Ngfi Protein, zif-268 Protein, EGR1 Protein, EGR-1-A Protein, Xegr-1 Protein, at225 Protein, egr-1 Protein, egr1 Protein, g0s30 Protein, krox-24 Protein, ngfi-a Protein, tis8 Protein, znf225 Protein, krox24 Protein, wu:fj64b05 Protein, wu:fq25f01 Protein, EGR-1 Protein, zenk Protein, EGR-1-B Protein, egr1-a Protein, egr1-b Protein, early growth response 1 Protein, early growth response protein 1 (egr-1) Protein, early growth response 1 L homeolog Protein, early growth response 1 S homeolog Protein, EGR1 Protein, CNK00890 Protein, Egr1 Protein, egr1.L Protein, egr1 Protein, egr1.S Protein
    Sub Type
    Fusionprotein
    Background
    EGR-1 belongs to the EGR family of C2H2-type zinc finger proteins. It is a nuclear protein and functions as a transcriptional regulator. EGR-1 recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site).The products of target genes it activates are required for differentiation and mitogenesis. Studies suggest this is a tumor suppressor gene. EGR-1 has a distinct pattern of expression in the brain, and its induction has been shown to be associated with neuronal activity. Several studies suggest it has a role in neuronal plasticity. EGR-1 has also been found to regulate the expression of synaptobrevin II (a protein important for synaptic exocytosis).
    Alternative Names: EGR-1, Early growth response protein 1, Zif268, zinc finger protein 225, NGFI-A , nerve growth factor-induced protein A,
    Molecular Weight
    19.9 kDa
    UniProt
    P18146
    Pathways
    Regulation of Carbohydrate Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
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