ZNHIT1 Protein (AA 1-154) (His tag)

Catalog No. ABIN1692473

Product Details

Target: ZNHIT1 (Zinc Finger, HIT-Type Containing 1 (ZNHIT1))

Protein Type: Recombinant

Protein Characteristics: AA 1-154

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This ZNHIT1 protein is labelled with His tag.

Purpose: Recombinant Human Zinc Finger HIT Domain-Containing Protein 1/ZNHIT1/ZNFN4A1 (N-6His)

Sequence: MGSSHHHHHH SSGLVPRGSH MVEKKTSVRS QDPGQRRVLD RAARQRRINR QLEALENDNF QDDPHAGLPQ LGKRLPQFDD DADTGKKKKK TRGDHFKLRF RKNFQALLEE QNLSVAEGPN YLTACAGPPS RPQRPFCAVC GFPSPYTCVS CGARYCTVRC LGTHQETRCL KWTV

Characteristics: Recombinant Human Zinc finger HIT domain-containing protein 1/ZNHIT1 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Val154) of Human ZNHIT1 fused with a 6His tag at the N-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl,50 % Glycerol, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: -80 °C

Storage Comment: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: ZNHIT1 (Zinc Finger, HIT-Type Containing 1 (ZNHIT1))

Alternative Name: ZNHIT1 (ZNHIT1 Products)

Synonyms: CG1I Protein, ZNFN4A1 Protein, 2700001K05Rik Protein, zgc:112524 Protein, cg1i Protein, znfn4a1 Protein, zinc finger HIT-type containing 1 Protein, zinc finger, HIT domain containing 1 Protein, zinc finger, HIT-type containing 1 Protein, ZNHIT1 Protein, Znhit1 Protein, znhit1 Protein

Sub Type: Fusionprotein

Background: ZNHIT1 belongs to the ZNHIT1 family and contains one HIT-type zinc finger. It can be phosphorylated on Thr by MAPK11 or MAPK14. ZNHIT1 is a component of the chromatin-remodeling SRCAP complex, which is composed of at least SRCAP, DMAP, RUVBL1, RUVBL2, ACTL6A, YEATS4, ACTR6 and ZNHIT1. ZNHIT1 may play a role in p53-mediated apoptosis induction.
Alternative Names: inc finger HIT domain-containing protein 1, cyclin-G1-binding protein 1, zinc finger protein subfamily 4A member 1, p18 hamlet, CGBP1, ZNFN4A1, ZNHIT1

Molecular Weight: 19.6 kDa

UniProt: O43257