UPRT Protein (AA 1-309) (His tag)
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- Target See all UPRT Proteins
- UPRT (Uracil phosphoribosyltransferase (FUR1) Homolog (UPRT))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-309
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This UPRT protein is labelled with His tag.
- Purpose
- Recombinant Human Uracil Phosphoribosyltransferase Homolog/UPRT (N-6His)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MATELQCPDS MPCHNQQVNS ASTPSPEQLR PGDLILDHAG GNRASRAKVI LLTGYAHSSL PAELDSGACG GSSLNSEGNS GSGDSSSYDA PAGNSFLEDC ELSRQIGAQL KLLPMNDQIR ELQTIIRDKT ASRGDFMFSA DRLIRLVVEE GLNQLPYKEC MVTTPTGYKY EGVKFEKGNC GVSIMRSGEA MEQGLRDCCR SIRIGKILIQ SDEETQRAKV YYAKFPPDIY RRKVLLMYPI LSTGNTVIEA VKVLIEHGVQ PSVIILLSLF STPHGAKSII QEFPEITILT TEVHPVAPTH FGQKYFGTD
- Characteristics
- Recombinant Human Uracil phosphoribosyltransferase homolog/UPRT is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Asp309) of Human UPRT fused with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product UPRT Protein
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Uracil phosphoribosyltransferase (FUR1) Homolog (UPRT) (AA 1-309) protein (His tag)
UPRT Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Uracil phosphoribosyltransferase (FUR1) Homolog (UPRT) (AA 1-309) protein (GST tag)UPRT Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Uracil phosphoribosyltransferase (FUR1) Homolog (UPRT) (AA 1-309) protein (Strep Tag)Crystallography grade UPRT Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Uracil phosphoribosyltransferase (FUR1) Homolog (UPRT) protein (Myc-DYKDDDDK Tag)UPRT Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,150 mM NaCl pH 8.0.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- UPRT (Uracil phosphoribosyltransferase (FUR1) Homolog (UPRT))
- Alternative Name
- UPRT (UPRT Products)
- Synonyms
- Gm774 Protein, FUR1 Protein, UPP Protein, uracil phosphoribosyltransferase Protein, uracil phosphoribosyltransferase homolog Protein, Uprt Protein, UPRT Protein
- Sub Type
- Fusionprotein
- Background
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UPRT is a cytoplasmic enzyme which belongs to the UPRTase family. UPRT is highly expressed in leukocytes, liver, spleen and thymus, with lower expression in brain, lung and skeletal muscle. UPRTcatalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. UPRT is a potential target for rational design of drugs to treat parasitic infections and cancer
Alternative Names: Uracil phosphoribosyltransferase homolog, UPP, FUR1, UPRT - Molecular Weight
- 35.9 kDa
- UniProt
- Q96BW1
- Pathways
- Ribonucleoside Biosynthetic Process
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