CD48 Protein (CD48) (AA 27-220) (Fc Tag,His tag)

Catalog No. ABIN1880630

Product Details

Target: CD48

Protein Type: Recombinant

Protein Characteristics: AA 27-220

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This CD48 protein is labelled with Fc Tag,His tag.

Purpose: Recombinant Human SLAM Family Member 2/CD48 (C-Fc-6His)

Sequence: QGHLVHMTVV SGSNVTLNIS ESLPENYKQL TWFYTFDQKI VEWDSRKSKY FESKFKGRVR LDPQSGALYI SKVQKEDNST YIMRVLKKTG NEQEWKIKLQ VLDPVPKPVI KIEKIEDMDD NCYLKLSCVI PGESVNYTWY GDKRPFPKEL QNSVLETTLM PHNYSRCYTC QVSNSVSSKN GTVCLSPPCT LARSVDDIEG RMDEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSREEMTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H

Characteristics: Recombinant Human CD48/SLAMF2 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Gln27­Ser220) of Human CD48SLAMF2 fused with a FC-6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.2.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: CD48

Alternative Name: CD48/SLAMF2 (CD48 Products)

Synonyms: AI449234 Protein, AW610730 Protein, BCM1 Protein, BLAST Protein, BLAST-1 Protein, BLAST1 Protein, Bcm-1 Protein, MEM-102 Protein, SLAMF2 Protein, Sgp-60 Protein, hCD48 Protein, mCD48 Protein, CD48 antigen Protein, Cd48 molecule Protein, CD48 molecule Protein, Cd48 Protein, CD48 Protein

Sub Type: Fusionprotein

Background: CD48 antigen, also known as B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, Leukocyte antigen MEM-102, TCT.1, CD48, BCM1,and BLAST1. CD48 contains one Ig-like C2-type domain and one Ig-like V-type domain, but does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. CD48 may facilitate interaction between activated lymphocytes and be involved in regulating T-cell activation. CD48 plays a vital role as an environmental sensor for regulating progenitor cell numbers and inhibiting tumor development. It is suggested that the anti-CD48 mAb has the potential to become an effective therapeutic mAb against multiple myeloma.
Alternative Names: CD48 antigen, B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, Leukocyte antigen MEM-102, TCT.1, CD48, BCM1,BLAST1

Molecular Weight: 53.1 kDa

UniProt: P09326