LILRA3 Protein (AA 19-439) (His tag)

Catalog No. ABIN1880684

Product Details

Target: LILRA3 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 (LILRA3))

Protein Type: Recombinant

Protein Characteristics: AA 19-439

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This LILRA3 protein is labelled with His tag.

Purpose: Recombinant Human Leukocyte Ig-Like Receptor A3/LILRA3/ILT6/CD85e (C-6His)

Sequence: THVQAGPLPK PTLWAEPGSV ITQGSPVTLR CQGSLETQEY HLYREKKTAL WITRIPQELV KKGQFPILSI TWEHAGRYCC IYGSHTVGLS ESSDPLELVV TGAYSKPTLS ALPSPVVTSG GNVTIQCDSQ VAFDGFILCK EGEDEHPQCL NSHSHARGSS RAIFSVGPVS PSRRWSYRCY GYDSRAPYVW SLPSDLLGLL VPGVSKKPSL SVQPGPVVAP GEKLTFQCGS DAGYDRFVLY KEWGRDFLQR PGRQPQAGLS QANFTLGPVS RSYGGQYTCS GAYNLSSEWS APSDPLDILI TGQIRARPFL SVRPGPTVAS GENVTLLCQS QGGMHTFLLT KEGAADSPLR LKSKRQSHKY QAEFPMSPVT SAHAGTYRCY GSLSSNPYLL THPSDPLELV VSGAAETLSP PQNKSDSKAG EVDHHHHHH

Characteristics: Recombinant Human ILT6/CD85e is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Thr19-Glu439) of Human ILT6 fused with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: LILRA3 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (Without TM Domain), Member 3 (LILRA3))

Alternative Name: ILT6/CD85e (LILRA3 Products)

Synonyms: CD85E Protein, HM31 Protein, HM43 Protein, ILT-6 Protein, ILT6 Protein, LIR-4 Protein, LIR4 Protein, e3 Protein, leukocyte immunoglobulin like receptor A3 Protein, LILRA3 Protein

Sub Type: Fusionprotein

Background: Leukocyte immunoglobulin-like receptor subfamily A member 3 is also known as CD85 antigen-like family member E, Immunoglobulin-like transcript 6, ILT-6, Leukocyte immunoglobulin-like receptor 4, LIR-4 and Monocyte inhibitory receptor HM43/HM31. In humans, it is encoded by the LILRA3 gene. It acts as soluble receptor for class I MHC antigens. Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2.It is detected in B-cells, natural killer (NK) cells, peripheral blood monocytes and lung.
Alternative Names: Leukocyte immunoglobulin-like receptor subfamily A member 3 is also known as CD85 antigen-like family member E, Immunoglobulin-like transcript 6, ILT-6, Leukocyte immunoglobulin-like receptor 4, LIR-4 and Monocyte inhibitory receptor HM43/HM31.

Molecular Weight: 46.6 kDa

UniProt: Q8N6C8