RGMA Protein (AA 169-422) (His tag)
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- Target See all RGMA Proteins
- RGMA (RGM Domain Family, Member A (RGMA))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 169-422
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RGMA protein is labelled with His tag.
- Purpose
- Recombinant Human Repulsive Guidance Molecule A/RGMA (N-6His)
- Sequence
- MNHKVHHHHH HMPHLRTFTD RFQTCKVQGA WPLIDNNYLN VQVTNTPVLP GSAATATSKL TIIFKNFQEC VDQKVYQAEM DELPAAFVDG SKNGGDKHGA NSLKITEKVS GQHVEIQAKY IGTTIVVRQV GRYLTFAVRM PEEVVNAVED WDSQGLYLCL RGCPLNQQID FQAFHTNAEG TGARRLAAAS PAPTAPETFP YETAVAKCKE KLPVEDLYYQ ACVFDLLTTG DVNFTLAAYY ALEDVKMLHS NKDKLHLYER TRDLPG
- Characteristics
- Recombinant Human Repulsive guidance molecule A/RGM domain family member A is produced with our E. coli expression system. The target protein is expressed with sequence(AA 169-422) of human RGMA fused with a His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product RGMA Protein
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RGM Domain Family, Member A (RGMA) protein (His-Avi Tag)
RGMA Origin: Human Host: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
RGM Domain Family, Member A (RGMA) (AA 48-422) protein (His-Avi Tag,Biotin)RGMA Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
RGM Domain Family, Member A (RGMA) (AA 169-422) protein (His tag)RGMA Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
RGM Domain Family, Member A (RGMA) (AA 326-423) protein (GST tag)RGMA Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
RGM Domain Family, Member A (RGMA) (AA 169-424) protein (His tag)Crystallography grade RGMA Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
RGM Domain Family, Member A (RGMA) (AA 170-427) protein (His tag)Crystallography grade RGMA Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys
RGM Domain Family, Member A (RGMA) protein (Myc-DYKDDDDK Tag)RGMA Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- RGMA (RGM Domain Family, Member A (RGMA))
- Alternative Name
- Repulsive Guidance Molecule A/RGM Domain Family Member A (RGMA Products)
- Synonyms
- RGM Protein, BC059072 Protein, C230063O06 Protein, repulsive guidance molecule family member a Protein, repulsive guidance molecule family member A Protein, RGMA Protein, Rgma Protein
- Background
- Repulsive guidance molecule A（RGMA） is a cell membrane protein and belongs to the repulsive guidance molecule (RGM) family. It interacts with NEO1, BMP2 and BMP4. RGMA is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that forms after a brain injury. This protein may also function as a tumor suppressor in some cancers.
- Molecular Weight
- 29.8 kDa
- UniProt
- Q96B86
- Pathways
- Tube Formation
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