PPY Protein (AA 30-88) (His tag)

Catalog No. ABIN1945400

Product Details

Target: PPY (Pancreatic Polypeptide (PPY))

Protein Type: Recombinant

Protein Characteristics: AA 30-88

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This PPY protein is labelled with His tag.

Purpose: Recombinant Human Pancreatic Polypeptide/PPY (C-6His)

Sequence: APLEPVYPGD NATPEQMAQY AADLRRYINM LTRPRYGKRH KEDTLAFSEW GSPHAAVPRV DHHHHHH

Characteristics: Recombinant Human PPY is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (AA 30-88) of Human PPY fused with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: PPY (Pancreatic Polypeptide (PPY))

Alternative Name: Pancreatic Prohormone (PPY Products)

Synonyms: PPY Protein, PNP Protein, PP Protein, AV061413 Protein, IGSPP Protein, pancreatic polypeptide Protein, peptide YY Protein, PPY Protein, Ppy Protein, PYY Protein

Background: PPY belongs to the NPY family and is synthesized as a 95 aa polypeptide precursor in the pancreatic islets of Langerhans. It is cleaved into two peptide products, the active hormone of 36 aa and an icosapeptide of unknown function. The hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa.

Molecular Weight: 7.8 kDa

UniProt: P01298

Pathways: Feeding Behaviour