LTA4H Protein (AA 1-611) (His tag)

Catalog No. ABIN1945422

Product Details

Target: LTA4H (Leukotriene A4 Hydrolase (LTA4H))

Protein Type: Recombinant

Protein Characteristics: AA 1-611

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This LTA4H protein is labelled with His tag.

Purpose: Recombinant Human Leukotriene A-4 Hydrolase/LTA4H (C-6His)

Sequence: MPEIVDTCSL ASPASVCRTK HLHLRCSVDF TRRTLTGTAA LTVQSQEDNL RSLVLDTKDL TIEKVVINGQ EVKYALGERQ SYKGSPMEIS LPIALSKNQE IVIEISFETS PKSSALQWLT PEQTSGKEHP YLFSQCQAIH CRAILPCQDT PSVKLTYTAE VSVPKELVAL MSAIRDGETP DPEDPSRKIY KFIQKVPIPC YLIALVVGAL ESRQIGPRTL VWSEKEQVEK SAYEFSETES MLKIAEDLGG PYVWGQYDLL VLPPSFPYGG MENPCLTFVT PTLLAGDKSL SNVIAHEISH SWTGNLVTNK TWDHFWLNEG HTVYLERHIC GRLFGEKFRH FNALGGWGEL QNSVKTFGET HPFTKLVVDL TDIDPDVAYS SVPYEKGFAL LFYLEQLLGG PEIFLGFLKA YVEKFSYKSI TTDDWKDFLY SYFKDKVDVL NQVDWNAWLY SPGLPPIKPN YDMTLTNACI ALSQRWITAK EDDLNSFNAT DLKDLSSHQL NEFLAQTLQR APLPLGHIKR MQEVYNFNAI NNSEIRFRWL RLCIQSKWED AIPLALKMAT EQGRMKFTRP LFKDLAAFDK SHDQAVRTYQ EHKASMHPVT AMLVGKDLKV DVDHHHHHH

Characteristics: Recombinant Human Leukotriene A-4 hydrolase/LTA4H is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (AA 1-611) of Human LTA4H fused with a polyhistidine tag at the C-termin

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM MES,2 mM EDTA,20 % Glycerol, pH 5.0.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: -80 °C

Storage Comment: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: LTA4H (Leukotriene A4 Hydrolase (LTA4H))

Alternative Name: Leukotriene A-4 Hydrolase/LTA4H (LTA4H Products)

Synonyms: LTA4H Protein, zgc:85809 Protein, MGC78867 Protein, lta4h Protein, MGC69197 Protein, LOC732953 Protein, DDBDRAFT_0191291 Protein, DDBDRAFT_0216768 Protein, DDB_0191291 Protein, DDB_0216768 Protein, AmpT Protein, leukotriene A4 hydrolase Protein, leukotriene A4 hydrolase L homeolog Protein, Leukotriene A4 hydrolase Protein, LTA4H Protein, lta4h Protein, lta4h.L Protein, LOC732953 Protein, Shew185_1367 Protein, Sbal195_1406 Protein, XfasM23_0741 Protein, Sbal223_2977 Protein, lkhA Protein, Lta4h Protein

Background: LTA4H, which is short for Leukotriene A-4 hydrolase, is a 611 aa. protein. It belongs to the peptidase M1 family, and exists in cytoplasm. This protein has at least 4 isforms produced by alternative splicing, and two of them are expressed in monocytes, lymphocytes, neutrophils, reticulocytes, platelets and fibroblasts. LTA4H involves in lipid metabolism and leukotriene B4 biosynthesis. It is a epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. It also has aminopeptidase activity

Molecular Weight: 70.3 kDa

UniProt: P09960