Plasminogen Activator Inhibitor 2 (SERPINB2) (full length), (AA 1-415) (Active) protein (GST tag)

Details for Product No. ABIN2003170, Supplier: Log in to see
Protein Name
  • HsT1201
  • PAI
  • PAI-2
  • PAI2
  • PLANH2
  • LOC100101625
  • SERPINB2
  • Planh2
  • ovalbumin
  • Pai2a
  • serpin peptidase inhibitor, clade B (ovalbumin), member 2
  • plasminogen activator inhibitor 2
  • serine (or cysteine) peptidase inhibitor, clade B, member 2
  • SERPINB2
  • LOC100101625
  • Serpinb2
Protein Characteristics
full length, AA 1-415
11
9
4
2
1
1
1
1
1
1
Origin
Human
15
11
4
Source
Baculovirus infected Insect Cells
17
5
2
2
1
1
Protein Type
Recombinant
Biological Activity
Active
Purification tag / Conjugate
This SERPINB2 protein is labelled with GST tag.
Application
Functional Studies (Func), SDS-PAGE (SDS)
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Characteristics The recombinant human SERPINB2/GST chimera consists of 640 amino acids and predicts a molecular mass of 73 kDa. It migrates as an approximately 65 kDa band in SDS-PAGE under reducing conditions.

Protein Structure: A DNA sequence encoding the full length of human SERPINB2 (NP_002566.1) (Met 1-Pro 415) was fused with the GST tag at the N-terminus.
Predicted N-Term: Met
Purity > 95 % as determined by SDS-PAGE
Endotoxin Level < 1.0 EU per μg of the protein as determined by the LAL method
ProductDetails: Biological Activity Comment Immobilized human GST-SerpinB2 at 10 μg/ml (100 μl/well) can bind biotinylated human uPA-His , The EC50 of biotinylated human uPA-His is 10.24-23.88 ng/ml.
Background Synonyms: HsT1201,PAI,PAI-2,PAI2,PLANH2
Molecular Weight 73 kDa, 65 kDa
NCBI Accession NP_002566
Research Area Proteolysis / Ubiquitin, Innate Immunity
Pathways Autophagy
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Lyophilized
Buffer Lyophilized from sterile 50 mM Tris, 100 mM NaCl, pH 8.0, 0.5 mM Reduced Glutathione, 10 % glycerol, 0.5 mM PMSF
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
Handling Advice Avoid repeated freeze-thaw cycles. It is recommended that the protein be aliquoted for optimal storage.
Storage -20 °C,-80 °C
Storage Comment Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Expiry Date 12 months
Supplier Images
 image for Plasminogen Activator Inhibitor 2 (SERPINB2) (full length), (AA 1-415) (Active) protein (GST tag) (ABIN2003170) Plasminogen Activator Inhibitor 2 (SERPINB2) (full length), (AA 1-415) (Active) protein (GST tag)
Background publications Gillard, Scarff, Loveland, Ricardo, Bird: "Modulation and redistribution of proteinase inhibitor 8 (Serpinb8) during kidney regeneration." in: American journal of nephrology, Vol. 26, Issue 1, pp. 34-42, 2006

Gillard, Scarff, Loveland, Ricardo, Bird: "Modulation and redistribution of proteinase inhibitor 8 (Serpinb8) during kidney regeneration." in: American journal of nephrology, Vol. 26, Issue 1, pp. 34-42, 2006 (PubMed).

Rawlings, Tolle, Barrett: "Evolutionary families of peptidase inhibitors." in: The Biochemical journal, Vol. 378, Issue Pt 3, pp. 705-16, 2004

Rawlings, Tolle, Barrett: "Evolutionary families of peptidase inhibitors." in: The Biochemical journal, Vol. 378, Issue Pt 3, pp. 705-16, 2004 (PubMed).

Sumi, Ichikawa, Nakamura, Miura, Aoki: "Expression and characterization of pro alpha 2-plasmin inhibitor." in: Journal of biochemistry, Vol. 106, Issue 4, pp. 703-7, 1990

Sumi, Ichikawa, Nakamura, Miura, Aoki: "Expression and characterization of pro alpha 2-plasmin inhibitor." in: Journal of biochemistry, Vol. 106, Issue 4, pp. 703-7, 1990 (PubMed).