HTLV-1 p24 Core Protein
Origin: Human T-lymphotropic Virus (HTLV)
Host: Escherichia coli (E. coli)
Recombinant
Protein is >95 % pure (as determined by HPLC-C4, and 10 % PAGE).
ELISA, WB
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- Target
- HTLV-1 p24 Core
- Protein Type
- Recombinant
- Origin
- Human T-lymphotropic Virus (HTLV)
- Source
- Escherichia coli (E. coli)
- Application
- ELISA, Western Blotting (WB)
- Sequence
- MHHHHHHAMG IRMASQNRDP AATSVAAARK GAEPSGGAAR GPVGKRLQQE LMTLMMSGDK GISAFPESDN LFKWVGTIHG AAGTVYEDLR YKLSLEFPSG YPYNAPTVKF LTPCYHPNVD TQGNICLDIL KEKWSALYDV RTILLSIQSL LGEPNIDSPL NTHAAELWKN PTAFKKYLQE TYSKQVTSQE P
- Specificity
- The protein is immunoreactive with the sera of HTLV-I infected individuals.
- Purity
- Protein is >95 % pure (as determined by HPLC-C4, and 10 % PAGE).
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- Application Notes
- This protein makes a good antigen in ELISA and western blots and an excellent antigen in the early detection of HIV seroconvertors. It shows minimal specificity problems.
- Restrictions
- For Research Use only
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- Buffer
- 1.0 mg/mL in 50 mM Na-PO4, pH 6.0, containing 1 mM DTT and 1 mM EDTA
- Storage
- -20 °C
- Storage Comment
- Reagent is shipped at ambient temperature. Freeze upon arrival. Store at -20 °C. The protein will remain stable for five years if stored frozen and for six months if stored in solution at 4 °C.
- Expiry Date
- 60 months
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- Target
- HTLV-1 p24 Core
- Target Type
- Viral Protein
- Background
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Human T-Lymphocyte Virus (HTLV)-1 p24 Core is an E. coli-derived recombinant. The protein contains the full-length sequence of HTLV-I p24. Human T-lymphotropic virus (HTLV) belongs to the family Retroviridae, genus Deltaretrovirus. It is a human, single-stranded RNA retrovirus that causes T-cell leukemia and T-cell lymphoma in adults and may also be involved in certain demyelinating diseases. Adult T-lymphotropic virus (ATLV) is a strain of this disease that effect primarily adults. Capsid protein p24 probably forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex.
Synonyms: rHTLV-Ip24c, Major core protein p24, gag polyprotein
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