beta-2-Microglobulin (B2M) Protein

Details for Product No. ABIN2128137, Supplier: Log in to see
Protein Name
  • B2M
  • b2m
  • B2MG
  • Ly-m11
  • beta2-m
  • beta2m
  • b2m-W01
  • b2m-W03
  • b2m-Z01
  • b2m-Z02
  • b2m-Z03
  • bwm
  • wu:fa94c05
  • wu:fb10a09
  • beta-2-microglobulin
  • beta-2 microglobulin
  • Beta-2-microglobulin-like
  • B2M
  • b2m
  • B2m
  • LOC100350679
Origin
Human
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3
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2
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Source
Human
54
21
20
6
4
4
4
2
1
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Protein Type
Native
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Supplier
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Characteristics Purified native Human beta 2 Microglobulin protein
Protein Source: Urine of patients with chronic renal tubular proteinuria
Purity > 95 % pure
Sterility Sterile filtered
Grade High Purity Grade
Background Beta2 microglobulin also known as B2M is a component of MHC class I molecules, which are present on all nucleated cells (excludes red blood cells). In humans, the B2 microglobulin protein is encoded by the B2M gene.
Description: Urine of patients with chronic renal tubular proteinuria.
Alternative Names: beta Microglobulin 2 protein, beta 2 Microglobulin, beta Microglobulin-2, beta Microglobulin 2, beta chain of mhc class 1 proteins protein, beta Microglobulin-2 protein, Hdcma22p protein, beta 2 microglobulin precursor protein, B2M protein
Research Area Cardiovascular
Pathways TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Liquid
Buffer Sterile filtered liquid in 40 mM PBS, pH 7.2, with 150 mM NaCl, 0 M EDTA sodium salt, and 0.05 % Sodium azide.
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid repeated freeze/thaw cycles.
Storage 4 °C
Storage Comment Store at 4 °C.
Product cited in: Neethling, Ramakrishna, Keler, Buchli, Woodburn, Weidanz: "Assessing vaccine potency using TCRmimic antibodies." in: Vaccine, Vol. 26, Issue 25, pp. 3092-102, 2008 (PubMed).

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