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ANGPTL4 Protein (AA 166-406) (His tag)

ANGPTL4 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Catalog No. ABIN2180590
  • Target See all ANGPTL4 Proteins
    ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 166-406
    Origin
    • 11
    • 8
    • 3
    • 3
    • 3
    • 1
    Human
    Source
    • 11
    • 8
    • 3
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This ANGPTL4 protein is labelled with His tag.
    Sequence
    AA 166-406
    Characteristics
    This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 27.9 kDa. The protein migrates as 33-36 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Purity
    >95 % as determined by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product ANGPTL4 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    50 mM MOPS, 100 mM NaCl, pH 7.2
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))
    Alternative Name
    Angiopoietin-Like 4 (ANGPTL4 Products)
    Synonyms
    ANGPTL2 Protein, ARP4 Protein, FIAF Protein, HFARP Protein, NL2 Protein, PGAR Protein, pp1158 Protein, Arp4 Protein, Bk89 Protein, Fiaf Protein, Hfarp Protein, Ng27 Protein, Pgar Protein, Pgarg Protein, Pp1158 Protein, ANGPTL4 Protein, fiaf Protein, im:7144703 Protein, si:rp71-39b20.7 Protein, angiopoietin like 4 Protein, angiopoietin-like 4 Protein, ANGPTL4 Protein, Angptl4 Protein, angptl4 Protein
    Background
    Angiopoietin-related protein 4 (ANGPTL4) is also known as Hepatic fibrinogen / angiopoietin - related protein (HFARP), ARP4, PGAR. ANGPTL4 contains one fibrinogen C-terminal domain. ANGPTL4 is a homooligomer , and the homooligomer undergoes proteolytic processing to release its carboxyl fibrinogen-like domain, which circulates as a monomer. The homooligomer unprocessed form is able to interact with the extracellular matrix. ANGPTL4 may act as a regulator of angiogenesis and modulate tumorigenesis. ANGPTL4 inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action.
    Molecular Weight
    27.9 kDa
    NCBI Accession
    NP_647475
    Pathways
    Regulation of Lipid Metabolism by PPARalpha
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