BTLA Protein (AA 31-134) (Fc Tag)
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- Target See all BTLA Proteins
- BTLA (B and T Lymphocyte Associated (BTLA))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 31-134
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This BTLA protein is labelled with Fc Tag.
- Sequence
- AA 31-134
- Characteristics
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 38.7 kDa. The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >92 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product BTLA Protein
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B and T Lymphocyte Associated (BTLA) (AA 31-150) protein (Fc Tag)
BTLA Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
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B and T Lymphocyte Associated (BTLA) protein (mFc-His Tag)BTLA Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
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B and T Lymphocyte Associated (BTLA) protein (mFc Tag)BTLA Origin: Human Host: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE.
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B and T Lymphocyte Associated (BTLA) (AA 25-289) protein (His tag)BTLA Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS, Func
B and T Lymphocyte Associated (BTLA) (Active) protein (Fc Tag,ECD)BTLA Origin: Rat Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
B and T Lymphocyte Associated (BTLA) (Active) protein (Fc Tag)BTLA Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- BTLA (B and T Lymphocyte Associated (BTLA))
- Alternative Name
- BTLA (BTLA Products)
- Synonyms
- BTLA Protein, BTLA1 Protein, CD272 Protein, A630002H24 Protein, B and T lymphocyte associated Protein, BTLA Protein, Btla Protein
- Background
- B- and T-lymphocyte attenuator (BTLA) is also known as B- and T-lymphocyte-associated protein, CD antigen CD272. BTLA contains one Ig-like V-type (immunoglobulin-like) domain. As a lymphocyte inhibitory receptor, BTLA / CD272 inhibits lymphocytes during immune response. BTLA / CD272 can interact with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2, and interact with TNFRSF14/HVEM.
- Molecular Weight
- 38.7 kDa
- NCBI Accession
- NP_001078826
- Pathways
- Cancer Immune Checkpoints
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