Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

CA9 Protein (AA 38-414) (His tag)

CA9 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Catalog No. ABIN2180677
  • Target See all CA9 Proteins
    CA9 (Carbonic Anhydrase IX (CA9))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 38-414
    Origin
    • 20
    • 7
    • 2
    • 2
    Human
    Source
    • 19
    • 6
    • 4
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CA9 protein is labelled with His tag.
    Sequence
    AA 38-414
    Characteristics
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 41.2 kDa. The protein migrates as 53-54 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Purity
    >90 % as determined by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product CA9 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    20 mM MES, 100 mM NaCl, pH 6.5
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
  • Target
    CA9 (Carbonic Anhydrase IX (CA9))
    Alternative Name
    Carbonic Anhydrase IX (CA9 Products)
    Synonyms
    CA9 Protein, CAIX Protein, Ca9 Protein, MN/CA9 Protein, MN Protein, carbonic anhydrase 9 Protein, CA9 Protein, CAH9 Protein, Car9 Protein
    Background
    Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes. CAs form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs rather slowly in the absence of a catalyst. One of the functions of the enzyme in animals is to interconvert carbon dioxide and bicarbonate to maintain acid-base balance in blood and other tissues, and to help transport carbon dioxide out of tissues. The active site of most carbonic anhydrases contains a zinc ion. There are at least five distinct CA families (α, β, γ, δ and ε). Carbonic anhydrase 9 (CA9 / CAIX) is also known as Membrane antigen MN (MN), Renal cell carcinoma-associated antigen G250, which belongs to the alpha-carbonic anhydrase family. CA9 / CAIX with an optimal activity at pH 6.49. Reversible hydration of carbon dioxide. CA IX participates in pH regulation. CA9 may be involved in the control of cell proliferation and transformation. CA-IX appears to be a novel specific biomarker for a cervical neoplasia.
    Molecular Weight
    41.7 kDa
    NCBI Accession
    NP_001207
You are here:
Support