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CD58 Protein (CD58) (AA 29-215) (His tag)

CD58 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Catalog No. ABIN2180813
  • Target See all CD58 Proteins
    CD58
    Protein Type
    Recombinant
    Protein Characteristics
    AA 29-215
    Origin
    Human
    Source
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CD58 protein is labelled with His tag.
    Sequence
    AA 29-215
    Characteristics
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 22.3 kDa. The protein migrates as 30-45 kDa under reducing (R) condition (SDS-PAGE) due to differtent glycosylation.
    Purity
    >95 % as determined by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product CD58 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    CD58
    Alternative Name
    CD58 (CD58 Products)
    Synonyms
    LFA-3 Protein, LFA3 Protein, ag3 Protein, CD58 molecule Protein, CD58 Protein
    Background
    CD antigen CD58 is also known as Lymphocyte function-associated antigen 3 (LFA-3). CD58 is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. CD58 /LFA3 is ligand of the T-lymphocyte CD2 glycoprotein, which binds to CD2 (LFA-2) [3] on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. Polymorphisms in the CD58 gene are associated with increased risk for multiple sclerosis.
    Molecular Weight
    22.3 kDa
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