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CDH6 Protein (AA 19-615) (His tag)

CDH6 Origin: Human Host: HEK-293 Cells Recombinant >85 % as determined by SDS-PAGE.
Catalog No. ABIN2180863
  • Target See all CDH6 Proteins
    CDH6 (K-Cadherin (CDH6))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 19-615
    Origin
    • 12
    • 4
    • 2
    • 1
    • 1
    Human
    Source
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CDH6 protein is labelled with His tag.
    Sequence
    AA 19-615
    Characteristics
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 67.2 kDa. The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Purity
    >85 % as determined by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product CDH6 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
  • Target
    CDH6 (K-Cadherin (CDH6))
    Alternative Name
    Cadherin-6 (CDH6 Products)
    Synonyms
    KCAD Protein, K-cadherin Protein, cad6 Protein, cadherin-6 Protein, CAD6 Protein, c-cad6B Protein, cadherin 6 Protein, Cdh6 Protein, CDH6 Protein
    Background
    Cadherin-6 (CDH6) is also known as Kidney cadherin (K-cadherin or KCAD), is a a type II classical cadherin from the cadherin superfamily. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. CDH6 / KCAD contains five cadherin domains. CDH6 is highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression and also expressed in certain liver and kidney carcinomas.
    Molecular Weight
    67.2 kDa & 63.4 kDa
    Pathways
    Cell-Cell Junction Organization
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