FETUB Protein (AA 16-382) (His tag)
-
- Target See all FETUB Proteins
- FETUB (Fetuin B (FETUB))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 16-382
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This FETUB protein is labelled with His tag.
- Sequence
- AA 16-382
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 42.4 kDa. The protein migrates as 48-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >95 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product FETUB Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- 50 mM Tris, 150 mM NaCl, pH 8.0
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
-
- Target
- FETUB (Fetuin B (FETUB))
- Alternative Name
- Fetuin B (FETUB Products)
- Synonyms
- 16G2 Protein, Gugu Protein, IRL685 Protein, Fet Protein, Pp63 Protein, gugu Protein, fetuin-b Protein, FETUB Protein, 16g2 Protein, irl685 Protein, im:6910148 Protein, 2310011O17Rik Protein, AI255764 Protein, D17980 Protein, fetuin B Protein, fetuin B L homeolog Protein, fetuin beta Protein, FETUB Protein, Fetub Protein, fetub.L Protein, fetub Protein
- Background
- Fetuin-B (FETUB), a second member of the fetuin family in mammals, is also known as Fetuin-like protein IRL685, 16G2 and Gugu, which is expressed in liver and testis and contains 2 cystatin fetuin-B-type domains. FETUB is a protease inhibitor required for egg fertilization. FETUB is also required to prevent premature zona pellucida hardening before fertilization, probably by inhibiting the protease activity of ASTL, a protease that mediates the cleavage of ZP2 and triggers zona pellucida hardening (By similarity). As a liver-derived plasma protein, FETUB is essential for fertilization.
- Molecular Weight
- 42.4 kDa
-