Fetuin A Protein (AA 19-367) (His tag)

Catalog No. ABIN2181088

Product Details

Target: Fetuin A (AHSG) (alpha-2-HS-Glycoprotein (AHSG))

Protein Type: Recombinant

Protein Characteristics: AA 19-367

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This Fetuin A protein is labelled with His tag.

Sequence: AA 19-367

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 38.2 kDa. The protein migrates as 55-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: >98 % as determined by SDS-PAGE.

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4

Handling Advice: Please avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).

Target Details

Target: Fetuin A (AHSG) (alpha-2-HS-Glycoprotein (AHSG))

Alternative Name: Fetuin A (AHSG Products)

Synonyms: ahs Protein, a2hs Protein, hsga Protein, fetua Protein, wu:fb63g02 Protein, zgc:103687 Protein, AHSG Protein, MGC116429 Protein, A2HS Protein, AHS Protein, FETUA Protein, HSGA Protein, Aa2-066 Protein, pp63 Protein, alpha-2-HS-glycoprotein Protein, alpha 2-HS glycoprotein Protein, alpha-2-HS-glycoprotein 1 Protein, alpha-2-HS-glycoprotein L homeolog Protein, Cphamn1_1981 Protein, AHSG Protein, ahsg Protein, ahsg1 Protein, ahsg.L Protein, Ahsg Protein

Background: Alpha-2-HS-glycoprotein (AHSG) is also known as Alpha-2-Z-globulin, Ba-alpha-2-glycoprotein, Fetuin-A (FETUA), is a glycoprotein that is composed of two subunits, the A and B chains, belongs to the cystatin family of proteases inhibitors and the fetuin class of plasma binding proteins. AHSG / Fetuin A is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes/macrophages. Fetuins are carrier proteins like albumin. Fetuin-A / AHSG forms soluble complexes with calcium and phosphate and thus is a carrier of otherwise insoluble calcium phosphate. Thus AHSG / Fetuin A is a potent inhibitor of pathological calcification. Fetuin A / FETUA promotes phagocytosis of apoptotic cells and plays a role in bone development, calcium homeostasis and insulin sensitivity. Mice deficient in Fetuin-A show systemic calcification of soft tissues.

Molecular Weight: 38.2 kDa