HSP90AA1 Protein (AA 535-732) (GST tag)

Catalog No. ABIN2181231

Product Details

Target: HSP90AA1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1))

Protein Type: Recombinant

Protein Characteristics: AA 535-732

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This HSP90AA1 protein is labelled with GST tag.

Sequence: AA 535-732

Characteristics: This protein carries a GST tag at the N-terminus. The protein has a calculated MW of 49.3 kDa. The protein migrates as 49 kDa under reducing (R) condition (SDS-PAGE).

Purity: >85 % as determined by SDS-PAGE.

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1.0 EU per μg by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 50 mM HEPES, 150 mM NaCl, pH 7.0

Handling Advice: Please avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).

Target Details

Target: HSP90AA1 (Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 1 (HSP90AA1))

Alternative Name: HSP90AA1 (HSP90AA1 Products)

Synonyms: EL52 Protein, HSP86 Protein, HSP89A Protein, HSP90A Protein, HSP90N Protein, HSPC1 Protein, HSPCA Protein, HSPCAL1 Protein, HSPCAL4 Protein, HSPN Protein, Hsp89 Protein, Hsp90 Protein, LAP2 Protein, Hsp86 Protein, Hspca Protein, htpG Protein, 86kDa Protein, 89kDa Protein, AL024080 Protein, AL024147 Protein, Hsp86-1 Protein, hsp4 Protein, HSP90 Protein, HSP90AA1 Protein, fb17b01 Protein, hsp90 Protein, hsp90a Protein, hsp90a.1 Protein, hsp90alpha Protein, wu:fb17b01 Protein, zgc:86652 Protein, Hsp90alpha Protein, heat shock protein 90 alpha family class A member 1 Protein, heat shock protein 90, alpha (cytosolic), class A member 1 Protein, Heat Shock Protein 90, cytosolic Protein, heat shock protein 90A Protein, molecular chaperone Protein, heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1 Protein, heat shock protein HSP 90-alpha Protein, heat shock protein 90kDa alpha (cytosolic), class A member 1 Protein, HSP90AA1 Protein, Hsp90aa1 Protein, HSP90A Protein, hsp90A Protein, hsp90aa1.1 Protein, LOC108698781 Protein

Background: Heat shock protein HSP 90-alpha (HSP90AA1 or HSP90A) is also known as Heat shock 86 kDa (HSP 86 or HSP86), Renal carcinoma antigen NY-REN-38, HSPC1, HSPCA, EL52, HSP89A, HSP90N, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2, which belongs to the heat shock protein 90 family. HSP90AA1 undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. HSP90AA1 interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.

Molecular Weight: 49.3 kDa

NCBI Accession: NP_005339

Pathways: M Phase, Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals