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IFNAR1 Protein (AA 28-436) (Fc Tag)

IFNAR1 Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Catalog No. ABIN2181250
  • Target See all IFNAR1 Proteins
    IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 28-436
    Origin
    • 13
    • 7
    • 2
    • 1
    • 1
    • 1
    Human
    Source
    • 8
    • 5
    • 5
    • 3
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This IFNAR1 protein is labelled with Fc Tag.
    Sequence
    AA 28-436
    Characteristics
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 73.8 kDa. The protein migrates as 110-120 kDa under reducing (R) condition (SDS-PAGE) due to Glycosylation.
    Purity
    >90 % as determined by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IFNAR1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))
    Alternative Name
    IFNAR1 (IFNAR1 Products)
    Synonyms
    ifnar1 Protein, IFNAR1 Protein, CD118 Protein, Ifar Protein, Ifnar Protein, Ifrc Protein, Infar Protein, AVP Protein, IFN-alpha-REC Protein, IFNAR Protein, IFNBR Protein, IFRC Protein, IFN-R-1 Protein, interferon alpha and beta receptor subunit 1 Protein, interferon-alpha/beta receptor alpha chain-like Protein, interferon (alpha and beta) receptor 1 Protein, interferon alpha/beta receptor 1 Protein, IFNAR1 Protein, ifnar1 Protein, Ifnar1 Protein, LOC609830 Protein
    Background
    Interferon alpha/beta receptor 1 ( IFNAR1) is also known as Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1 (CRF2-1), Type I interferon receptor 1, IFNAR, which belongs to the type II cytokine receptor family. IFNAR1 /IFNAR contains four fibronectin type-III domains. IFNAR1 associates with IFNAR2 to form the type I interferon receptor. IFNAR1 is receptor for interferons alpha and beta. IFNAR1 can transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway.
    Molecular Weight
    73.8 kDa
    NCBI Accession
    NP_000620
    Pathways
    JAK-STAT Signaling, Hepatitis C
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