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IL27 Receptor alpha Protein (AA 33-514) (Fc Tag)

IL27RA Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Catalog No. ABIN2181379
  • Target See all IL27 Receptor alpha (IL27RA) Proteins
    IL27 Receptor alpha (IL27RA) (Interleukin 27 Receptor, alpha (IL27RA))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 33-514
    Origin
    • 8
    • 4
    • 1
    Human
    Source
    • 4
    • 4
    • 4
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IL27 Receptor alpha protein is labelled with Fc Tag.
    Sequence
    AA 33-514
    Characteristics
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 79 kDa. The protein migrates as 105-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Purity
    >95 % as determined by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IL27RA Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    IL27 Receptor alpha (IL27RA) (Interleukin 27 Receptor, alpha (IL27RA))
    Alternative Name
    IL-27 Ra (IL27RA Products)
    Synonyms
    IL27RA Protein, CRL1 Protein, IL-27RA Protein, IL27R Protein, TCCR Protein, WSX1 Protein, zcytor1 Protein, IL-27R Protein, Tccr Protein, WSX-1 Protein, Wsx1 Protein, interleukin 27 receptor subunit alpha Protein, interleukin-27 receptor subunit alpha Protein, interleukin 27 receptor, alpha Protein, IL27RA Protein, LOC484907 Protein, Il27ra Protein
    Background
    Interleukin-27 receptor subunit alpha ( IL27RA) is also known as Cytokine receptor WSX-1, Cytokine receptor-like 1, Type I T-cell cytokine receptor (TCCR), ZcytoR1, IL27RA belongs to the type I cytokine receptor family and type 2 subfamily. IL27RA contains three fibronectin type-III domains. IL27RA is highly expressed in lymphoid tissues such as spleen, lymph nodes and peripheral blood leukocytes. IL27RA is receptor for IL27, but requires IL6ST/gp130 to mediate signal transduction in response to IL27. IL27RA involved in the regulation of Th1-type immune responses. IL27RA also appears to be involved in innate defense mechanisms.
    Molecular Weight
    78.9 kDa
    Pathways
    Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response
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