LBP Protein (AA 26-481) (His tag)
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- Target See all LBP Proteins
- LBP (Lipopolysaccharide Binding Protein (LBP))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 26-481
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LBP protein is labelled with His tag.
- Sequence
- AA 26-481
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 52.8 kDa. The protein migrates as 62 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >95 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product LBP Protein
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Lipopolysaccharide Binding Protein (LBP) (AA 26-477) protein (GST tag)
LBP Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Lipopolysaccharide Binding Protein (LBP) (AA 26-481) protein (His tag)Crystallography grade LBP Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- LBP (Lipopolysaccharide Binding Protein (LBP))
- Alternative Name
- Lipopolysaccharide-Binding Protein / LBP (LBP Products)
- Synonyms
- BPIFD2 Protein, Bpifd2 Protein, Ly88 Protein, LPSBP Protein, LBP Protein, lipopolysaccharide binding protein Protein, lipopolysaccharide-binding protein Protein, LBP Protein, Lbp Protein, LOC100472839 Protein
- Background
- Lipopolysaccharide-binding protein (LBP),a member of the BPI/LBP/Plunc superfamily, BPI/LBP family, is detected in blood serum. LBP plays a role in the innate immune response. Alao,LBP can bind to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria, and act as an affinity enhancer for CD14, facilitating its association with LPS. Furthermore, LBP is able to promote the release of cytokines in response to bacterial lipopolysaccharide.
- Molecular Weight
- 52.8 kDa
- UniProt
- P18428
- Pathways
- TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process
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