LRRC4 Protein (AA 39-527) (His tag)
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- Target See all LRRC4 Proteins
- LRRC4 (Leucine Rich Repeat Containing 4 (LRRC4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 39-527
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LRRC4 protein is labelled with His tag.
- Sequence
- AA 39-527
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 55.6 kDa. The protein migrates as 90-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >92 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product LRRC4 Protein
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Leucine Rich Repeat Containing 4 (LRRC4) (AA 549-653) protein (His tag)
Crystallography grade LRRC4 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Leucine Rich Repeat Containing 4 (LRRC4) (AA 548-652) protein (His tag)Crystallography grade LRRC4 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Leucine Rich Repeat Containing 4 (LRRC4) (AA 39-527) protein (His tag)Crystallography grade LRRC4 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Leucine Rich Repeat Containing 4 (LRRC4) (AA 41-526) protein (His tag)Crystallography grade LRRC4 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Leucine Rich Repeat Containing 4 (LRRC4) (AA 39-653) protein (rho-1D4 tag)Crystallography grade LRRC4 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
Leucine Rich Repeat Containing 4 (LRRC4) (AA 41-652) protein (rho-1D4 tag)Crystallography grade LRRC4 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, Crys, SDS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- LRRC4 (Leucine Rich Repeat Containing 4 (LRRC4))
- Alternative Name
- LRRC4 (LRRC4 Products)
- Synonyms
- NGL-2 Protein, MBAG1 Protein, NLG-2 Protein, Nag14 Protein, leucine rich repeat containing 4 Protein, LRRC4 Protein, Lrrc4 Protein
- Background
- LRRC4 (Leu-rich repeat/LRR-containing glycoprotein 4), LRRC4B and LRRC4C are post-synaptic adhesion molecules of the LRR protein family that induce excitatory synapse formation. LRRC4 is also known as Brain tumor-associated protein BAG, Netrin-G2 ligand (NGL-2), Nasopharyngeal carcinoma-associated gene 14 protein (NAG14), which contains 1 Ig-like (immunoglobulin-like) domain and 9 LRR (leucine-rich) repeats, 1 LRRCT domain, 1 LRRNT domain. LRRC4 / NGL-2 specifically expressed in brain. LRRC4 / NGL-2 regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. LRRC4 / NGL-2 organize the lamina/pathway-specific differentiation of dendrites. LRRC4 / NGL-2 plays a important role for auditory synaptic responses and involved in the suppression of glioma.
- Molecular Weight
- 55.8 kDa
- Pathways
- Synaptic Membrane
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