LUM Protein (AA 19-338) (His tag)
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- Target See all LUM Proteins
- LUM (Lumican (LUM))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-338
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LUM protein is labelled with His tag.
- Sequence
- AA 19-338
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 37.5 kDa. The protein migrates as 50-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >95 % as determined by reduced SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product LUM Protein
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Lumican (LUM) (AA 1-338) protein (GST tag)
LUM Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Lumican (LUM) protein (His tag)LUM Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Lumican (LUM) (AA 15-338) protein (His tag)LUM Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Lumican (LUM) (AA 19-338) protein (His tag)Crystallography grade LUM Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Lumican (LUM) (AA 19-338) protein (His tag)Crystallography grade LUM Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- LUM (Lumican (LUM))
- Alternative Name
- Lumican (LUM Products)
- Synonyms
- MGC64527 Protein, zgc:86661 Protein, ldc Protein, slrr2d Protein, DKFZp468L1116 Protein, LDC Protein, SLRR2D Protein, Ldc Protein, lumican Protein, lumican L homeolog Protein, LUM Protein, lum.L Protein, lum Protein, CpipJ_CPIJ010209 Protein, Lum Protein
- Background
- Lumican (LUM) is also known as Keratan sulfate proteoglycan lumican, KSPG lumican,LDC and SLRR2D, which belongs to the small leucine-rich proteoglycan (SLRP) family and SLRP class II subfamily. LUM /Lumican is present in the extracellular matrix of human articular cartilage at all ages, although its abundance is far greater in the adult. In the adult cartilage LUM /Lumican exists predominantly in a glycoprotein form lacking keratan sulfate, whereas the juvenile form of the molecule is a proteoglycan. LUM participates in the maintenance of tissue homeostasis and modulates cellular functions including cell proliferation, migration, and differentiation. The expression of LUM has been correlated to the growth and metastasis of various malignancies.
- Molecular Weight
- 37.5 kDa
- NCBI Accession
- NP_002336
- Pathways
- Glycosaminoglycan Metabolic Process
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