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NCR1 Protein (AA 22-254) (Fc Tag)

NCR1 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Catalog No. ABIN2181529
  • Target See all NCR1 Proteins
    NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 22-254
    Origin
    • 12
    • 8
    • 5
    • 2
    • 1
    Human
    Source
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This NCR1 protein is labelled with Fc Tag.
    Sequence
    AA 22-254
    Characteristics
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 53 kDa. The protein migrates as 53-75 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Purity
    >95 % as determined by SDS-PAGE.
    Sterility
    0.22 μm filtered
    Endotoxin Level
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product NCR1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    Handling Advice
    Please avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))
    Alternative Name
    NKp46 (NCR1 Products)
    Synonyms
    CD335 Protein, LY94 Protein, NK-p46 Protein, NKP46 Protein, Ly94 Protein, NKp46 Protein, KILR-1 Protein, Nk-p46 Protein, Nkp46 Protein, natural cytotoxicity triggering receptor 1 Protein, NCR1 Protein, Ncr1 Protein
    Background
    Natural cytotoxicity triggering receptor 1 (NCR1) is also known as Natural killer cell p46-related protein (NK-p46), Lymphocyte antigen 94 homolog (LY94), CD antigen CD335, which belongs to the natural cytotoxicity receptor (NCR) family. NCR1 contains two Ig-like (immunoglobulin-like) domains. NCR1 interacts with CD247 and FCER1G. NCR1 / CD335 may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
    Molecular Weight
    53.0 kDa
    Pathways
    Regulation of Leukocyte Mediated Immunity
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