CLEC4G Protein (AA 55-293) (Fc Tag)
(1 reference)-
- Target See all CLEC4G Proteins
- CLEC4G (C-Type Lectin Domain Family 4, Member G (CLEC4G))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 55-293
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CLEC4G protein is labelled with Fc Tag.
- Sequence
- AA 55-293
- Characteristics
- This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 52.1 kDa. The protein migrates as 65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >85 % as determined by SDS-PAGE.
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product CLEC4G Protein
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C-Type Lectin Domain Family 4, Member G (CLEC4G) (AA 53-293) protein (His tag)
Crystallography grade CLEC4G Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
C-Type Lectin Domain Family 4, Member G (CLEC4G) (AA 52-294) protein (His tag)Crystallography grade CLEC4G Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS, Crys
C-Type Lectin Domain Family 4, Member G (CLEC4G) (AA 1-293) protein (Strep Tag)Crystallography grade CLEC4G Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
C-Type Lectin Domain Family 4, Member G (CLEC4G) (AA 1-294) protein (Strep Tag)Crystallography grade CLEC4G Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- 50 mM Tris, 100 mM Glycine, pH 7.5
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Lyophilized Protein should be stored at -20 °C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20 °C or -71 °C. Avoid repeated freeze-thaw cycles.
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: "Characterization of a novel anti-human lymphocyte activation gene 3 (LAG-3) antibody for cancer immunotherapy." in: mAbs, Vol. 11, Issue 6, pp. 1139-1148, (2019) (PubMed).
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: "Characterization of a novel anti-human lymphocyte activation gene 3 (LAG-3) antibody for cancer immunotherapy." in: mAbs, Vol. 11, Issue 6, pp. 1139-1148, (2019) (PubMed).
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- Target
- CLEC4G (C-Type Lectin Domain Family 4, Member G (CLEC4G))
- Alternative Name
- LSECtin (CLEC4G Products)
- Synonyms
- RGD1562320 Protein, DTTR431 Protein, LP2698 Protein, LSECtin Protein, UNQ431 Protein, 4930572L20Rik Protein, C-type lectin domain family 4 member G Protein, C-type lectin domain family 4, member G Protein, C-type lectin domain family 4, member g Protein, CLEC4G Protein, Clec4g Protein
- Background
- C-type lectin superfamily 4, member G (CLEC4G) is also known as liver and lymph node sinusoidal endothelial cell C-type lectin (LSECtin), which is a member of subgroup II of the C-type (Ca2+-dependent) lectin superfamily. CLEC4G / LSECtin binds to mannose, GlcNAc, and fucose in a Ca2+-dependent manner. In addition, CLEC4G / LSECtin has the ability to bind to surface glycoproteins of enveloped viruses. In particular, interaction of LSECtin with the surface glycoproteins of severe acute respiratory syndrome (SARS) coronavirus and Ebola virus has been described, and LSECtin-mediated infection of cells by Ebola virus has been demonstrated.
- Molecular Weight
- 52.1 kDa
- NCBI Accession
- NP_940894
- UniProt
- Q6UXB4
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