MTCH2 Protein (AA 29-174) (His tag)
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- Target See all MTCH2 Proteins
- MTCH2 (Mitochondrial Carrier 2 (MTCH2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 29-174
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This MTCH2 protein is labelled with His tag.
- Application
- Western Blotting (WB), ELISA, Mass Spectrometry (MS), Neutralization (Neut)
- Purity
- ~95 %
- Top Product
- Discover our top product MTCH2 Protein
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Mitochondrial Carrier 2 (MTCH2) (AA 1-303) protein (GST tag)
MTCH2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Mitochondrial Carrier 2 (MTCH2) (AA 2-303) protein (rho-1D4 tag)Crystallography grade MTCH2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Mitochondrial Carrier 2 (MTCH2) (AA 2-303) protein (rho-1D4 tag)Crystallography grade MTCH2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
- This recombinant protein can be used for WB, ELISA, MS and neutralization assays.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 1X PBS containing 0.1 % SDS
- Handling Advice
- Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- Storage
- -80 °C
- Storage Comment
- Store in working aliquots at -70 °C.
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- Target
- MTCH2 (Mitochondrial Carrier 2 (MTCH2))
- Alternative Name
- MTCH2 (MTCH2 Products)
- Synonyms
- MIMP Protein, SLC25A50 Protein, Hspc032 Protein, fi20c06 Protein, fj35g12 Protein, wu:fi20c06 Protein, wu:fj35g12 Protein, 2310034D24Rik Protein, 4930539J07Rik Protein, HSPC032 Protein, mitochondrial carrier 2 Protein, mitochondrial carrier 2 L homeolog Protein, mitochondrial carrier homolog 2 Protein, MTCH2 Protein, mtch2.L Protein, Mtch2 Protein, mtch2 Protein
- Background
- Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer (reviewed in 1). The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death (reviewed in 2 and 3). MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals (4-6), suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway. The doublet observed in the SDS-PAGE is likely due to incomplete removal of the signal sequence.
- Molecular Weight
- 19 kDa (Calculated)
- Gene ID
- 56428
- NCBI Accession
- NP_055157
- OMIM
- 5815347
- UniProt
- Q791V5
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