Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

CNTN2 Protein (His tag)

CNTN2 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. WB Active
Catalog No. ABIN2566474
  • Target See all CNTN2 Proteins
    CNTN2 (Contactin 2 (Axonal) (CNTN2))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 7
    • 3
    Human
    Source
    • 3
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CNTN2 protein is labelled with His tag.
    Application
    Western Blotting (WB)
    Characteristics

    Measured by its ability to enhance neurite outgrowth of E16-E18 rat embryonic cortical neurons. Optimal neurite outgrowth was observed when neurons were plated on 96-well culture plates that had been precoated with 50 μL/well of the rhContactin2 solution at 8-30 μg/mL.

    Purity
    >95 % as determined by SDS-PAGE.
    Top Product
    Discover our top product CNTN2 Protein
  • Application Notes
    This recombinant protein can be used for WB. For research use only.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Storage
    -80 °C,-20 °C
    Storage Comment
    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
  • Target
    CNTN2 (Contactin 2 (Axonal) (CNTN2))
    Alternative Name
    Contactin 2 (CNTN2 Products)
    Synonyms
    tag1 Protein, si:dz37k09.2 Protein, CNTN2 Protein, D130012K04Rik Protein, TAG-1 Protein, Tax Protein, AXT Protein, TAX Protein, TAX1 Protein, AXONIN-1 Protein, TAG-564 Protein, TAG1 Protein, contactin 2 Protein, contactin 2 (axonal) Protein, cntn2 Protein, CNTN2 Protein, Cntn2 Protein
    Background
    Contactin-2 is also known as CNTN2, TAX1 (transiently-expressed axonal glycoprotein), TAG1 (transient axonal glycoprotein), and axonin-1, and is a member of the immunoglobulin superfamily. CNTN2 consists of six Ig-like domains and four fibronectin type III domains, and is anchored to the membrane by glycosylphosphatidylinositol (GPI), whereas the soluble form can be released by a GPI-specific phospholipase. As a neural cell adhesion molecule expressed by a subset of neuronal populations in the developing CNS and PNS, CNTN2 mediates cell-cell interactions either via homophilic, or heterophilic contacts with various adhesion molecules including NgCAM, NrCAM, NCAM and neurocan. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. It may also be involved in glial tumorigenesis and may provide a potential target for therapeutic intervention.
    Molecular Weight
    109 kDa
    Gene ID
    6900
    NCBI Accession
    NP_005067
    UniProt
    Q02246
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size
You are here:
Support