LILRB2 Protein (His tag)
-
- Target See all LILRB2 Proteins
- LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))
- Protein Type
- Recombinant
- Biological Activity
- Active
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LILRB2 protein is labelled with His tag.
- Application
- Western Blotting (WB)
- Characteristics
-
Measured by its ability of the immobilized protein to support the adhesion of HSB2 human peripheral blood acute lymphoblastic leukemia cells. When 80000 cells/well are added to LILRB2 coated plates (8. 8 μg/mL with 100μL/well), > 40 % cells will adhere for 1 hour incubation at 37˚,C.
- Purity
- >92 % as determined by SDS-PAGE.
- Top Product
- Discover our top product LILRB2 Protein
-
-
- Application Notes
- This recombinant protein can be used for WB. For research use only.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -80 °C,-20 °C
- Storage Comment
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
-
- Target
- LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))
- Alternative Name
- LILRB2 (LILRB2 Products)
- Synonyms
- CD85D Protein, ILT-4 Protein, ILT4 Protein, LIR-2 Protein, LIR2 Protein, MIR-10 Protein, MIR10 Protein, leukocyte immunoglobulin-like receptor subfamily A member 3 Protein, leukocyte immunoglobulin like receptor B2 Protein, LOC100433990 Protein, LILRB2 Protein
- Background
- Leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2) is also known as CD85 antigen-like family member D (CD85d), Immunoglobulin-like transcript 4 (ILT-4), Monocyte / macrophage immunoglobulin-like receptor 10 (MIR-10), which is a member of the the subfamily B class of LIR receptors. LILRB2 is receptor for class I MHC antigens. LILRB2 recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB2 competes with CD8A for binding to class I MHC antigens. LILRB2 / CD85d inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
- Molecular Weight
- 48.6 kDa
- Gene ID
- 10288
- UniProt
- Q8N423
- Pathways
- Cellular Response to Molecule of Bacterial Origin
-