RSPO1 Protein (His tag)
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- Target See all RSPO1 Proteins
- RSPO1 (R-Spondin 1 (RSPO1))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This RSPO1 protein is labelled with His tag.
- Application
- Western Blotting (WB), ELISA
- Characteristics
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Measured by its binding ability in a functional ELISA. Immobilized human RSPO1 at 20 μg/mL (100 μL/well ) can bind human LIMPII with a linear ranger of 31. 25 - 1000 ng/mL.
- Purity
- >95 % as determined by SDS-PAGE.
- Top Product
- Discover our top product RSPO1 Protein
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R-Spondin 1 (RSPO1) protein (His tag)
RSPO1 Origin: Human Host: CHO Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
R-Spondin 1 (RSPO1) (AA 21-263) protein (His tag)RSPO1 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
R-Spondin 1 (RSPO1) (AA 21-265) protein (His tag)RSPO1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
R-Spondin 1 (RSPO1) (AA 21-146) protein (His tag)RSPO1 Origin: Human Host: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
R-Spondin 1 (RSPO1) (Active) protein (His tag)RSPO1 Origin: Mouse Host: CHO Cells Recombinant > 95 % as determined by SDS-PAGE Active
R-Spondin 1 (RSPO1) (AA 21-263) protein (His tag)Crystallography grade RSPO1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
R-Spondin 1 (RSPO1) (AA 21-265) protein (His tag)Crystallography grade RSPO1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
- This recombinant protein can be used for WB, ELISA. For research use only.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -80 °C,-20 °C
- Storage Comment
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
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- Target
- RSPO1 (R-Spondin 1 (RSPO1))
- Alternative Name
- Rspondin 1 (RSPO1 Products)
- Synonyms
- RGD1565558 Protein, CRISTIN3 Protein, RSPO Protein, R-spondin Protein, Rspondin Protein, wu:fj81e05 Protein, zgc:92153 Protein, R-spondin 1 Protein, Rspo1 Protein, RSPO1 Protein, LOC100049655 Protein, rspo1 Protein
- Background
- R-spondin-1 is also known as Roof plate-specific Spondin 1 (RSPO1) and cysteinerich and single thrombospondin domain containing protein 3 (Cristin 3), which is a secreted protein which belongs to the R-Spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. All Rspondins regulate Wnt/β-catenin signaling, but have distinct expression patterns. Like other R-Spondins, R-Spondin-1 contains two adjacent cysteinerich furinlike domains (aa 34-135) with one potential N-glycosylation site, followed by a thrombospondin (TSP1) motif (aa 147-207) and a region rich in basic residues (aa 211-263). Only the furinlike domains are needed for β-catenin stabilization. A putative nuclear localization signal at the C-terminus may allow some expression in the nucleus.
- Molecular Weight
- 27.6 kDa
- Gene ID
- 284654
- UniProt
- Q2MKA7
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